The Medical Necessity of Comprehensive Patch Testing.
Allergic contact dermatitis is associated with significant disease and economic burden in the United States. To properly manage allergic contact dermatitis, it is important to accurately identify the substance(s) implicated in the dermatitis to prevent disease recurrence. The commercially available T.R.U.E Test (36 allergens) screening panel has been reported to have a conservative hypothetical allergen detection rate of 66.0%, at most. Importantly, these calculations are based on the 78% of patients who had clinically relevant reactions to allergens present on the North American Contact Dermatitis Group screening series (70 allergens), without the use of supplemental allergens. Testing with supplemental allergens beyond a screening series can more fully evaluate an individual's environmental and occupational exposure, which may significantly increase diagnostic accuracy. Comprehensive patch testing with additional allergens in sunscreens, cosmetics, and fragrances, for example, may increase the diagnostic yield as well as the likelihood of achieving a cure if the dermatitis is chronic and recalcitrant.
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- Patch Tests
- Humans
- Dermatology & Venereal Diseases
- Dermatitis, Allergic Contact
- 3204 Immunology
- 3202 Clinical sciences
- 1103 Clinical Sciences
Citation
Published In
DOI
EISSN
ISSN
Publication Date
Volume
Issue
Start / End Page
Related Subject Headings
- Patch Tests
- Humans
- Dermatology & Venereal Diseases
- Dermatitis, Allergic Contact
- 3204 Immunology
- 3202 Clinical sciences
- 1103 Clinical Sciences