Cooling the Itch via TRPM8.
Publication
, Journal Article
Liu, B; Jordt, S-E
Published in: J Invest Dermatol
June 2018
Cooling is an effective temporary remedy for itch, bringing welcome relief to itchy insect bites, nettle stings, poison ivy, atopic dermatitis, and psoriasis. Menthol, causing a cooling sensation, has similar itch-relieving effects. Palkar et al. demonstrate that TRPM8, a menthol- and cold-activated ion channel, is essential for cooling to relieve itch, suggesting that pharmacologic TRPM8 activation should be explored further as an antipruritic strategy.
Duke Scholars
Altmetric Attention Stats
Dimensions Citation Stats
Published In
J Invest Dermatol
DOI
EISSN
1523-1747
Publication Date
June 2018
Volume
138
Issue
6
Start / End Page
1254 / 1256
Location
United States
Related Subject Headings
- TRPM Cation Channels
- Neurons
- Menthol
- Dermatology & Venereal Diseases
- 3202 Clinical sciences
- 1112 Oncology and Carcinogenesis
- 1103 Clinical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Liu, B., & Jordt, S.-E. (2018). Cooling the Itch via TRPM8. J Invest Dermatol, 138(6), 1254–1256. https://doi.org/10.1016/j.jid.2018.01.020
Liu, Boyi, and Sven-Eric Jordt. “Cooling the Itch via TRPM8.” J Invest Dermatol 138, no. 6 (June 2018): 1254–56. https://doi.org/10.1016/j.jid.2018.01.020.
Liu B, Jordt S-E. Cooling the Itch via TRPM8. J Invest Dermatol. 2018 Jun;138(6):1254–6.
Liu, Boyi, and Sven-Eric Jordt. “Cooling the Itch via TRPM8.” J Invest Dermatol, vol. 138, no. 6, June 2018, pp. 1254–56. Pubmed, doi:10.1016/j.jid.2018.01.020.
Liu B, Jordt S-E. Cooling the Itch via TRPM8. J Invest Dermatol. 2018 Jun;138(6):1254–1256.
Published In
J Invest Dermatol
DOI
EISSN
1523-1747
Publication Date
June 2018
Volume
138
Issue
6
Start / End Page
1254 / 1256
Location
United States
Related Subject Headings
- TRPM Cation Channels
- Neurons
- Menthol
- Dermatology & Venereal Diseases
- 3202 Clinical sciences
- 1112 Oncology and Carcinogenesis
- 1103 Clinical Sciences