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The effect of pre-eclampsia on retinal microvascular caliber at delivery and post-partum

Publication ,  Journal Article
Soma-Pillay, P; Pillay, R; Wong, TY; Makin, JD; Pattinson, RC
Published in: Obstetric Medicine
September 1, 2018

Background: The retinal microcirculation provides a unique view of microvessel structure by means of non-invasive, retinal image analysis. The aim of the study was to compare the retinal vessel caliber at delivery and one-year post-partum between women who have had pre-eclampsia during pregnancy to a normotensive control group. Methods: Digital photos of the eye were taken at delivery and one-year post-partum. Retinal vessels were analysed and summarised as the corrected central retinal arteriolar equivalent and corrected central retinal venular equivalent. Results: The corrected central retinal arteriolar equivalent and corrected central retinal venular equivalent were significantly lower in the pre-eclamptic group compared to the control group both at delivery and one-year post-partum (p < 0.001). Conclusion: Retinal artery and venular caliber changes that occur during pregnancies affected by pre-eclampsia persist for up to one-year post-partum. These changes may reflect a permanent, long-term microvascular dysfunction and may be useful as a biomarker of future vascular risk.

Duke Scholars

Published In

Obstetric Medicine

DOI

EISSN

1753-4968

ISSN

1753-495X

Publication Date

September 1, 2018

Volume

11

Issue

3

Start / End Page

116 / 120

Related Subject Headings

  • 3215 Reproductive medicine
  • 1114 Paediatrics and Reproductive Medicine
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Soma-Pillay, P., Pillay, R., Wong, T. Y., Makin, J. D., & Pattinson, R. C. (2018). The effect of pre-eclampsia on retinal microvascular caliber at delivery and post-partum. Obstetric Medicine, 11(3), 116–120. https://doi.org/10.1177/1753495X17745727
Soma-Pillay, P., R. Pillay, T. Y. Wong, J. D. Makin, and R. C. Pattinson. “The effect of pre-eclampsia on retinal microvascular caliber at delivery and post-partum.” Obstetric Medicine 11, no. 3 (September 1, 2018): 116–20. https://doi.org/10.1177/1753495X17745727.
Soma-Pillay P, Pillay R, Wong TY, Makin JD, Pattinson RC. The effect of pre-eclampsia on retinal microvascular caliber at delivery and post-partum. Obstetric Medicine. 2018 Sep 1;11(3):116–20.
Soma-Pillay, P., et al. “The effect of pre-eclampsia on retinal microvascular caliber at delivery and post-partum.” Obstetric Medicine, vol. 11, no. 3, Sept. 2018, pp. 116–20. Scopus, doi:10.1177/1753495X17745727.
Soma-Pillay P, Pillay R, Wong TY, Makin JD, Pattinson RC. The effect of pre-eclampsia on retinal microvascular caliber at delivery and post-partum. Obstetric Medicine. 2018 Sep 1;11(3):116–120.
Journal cover image

Published In

Obstetric Medicine

DOI

EISSN

1753-4968

ISSN

1753-495X

Publication Date

September 1, 2018

Volume

11

Issue

3

Start / End Page

116 / 120

Related Subject Headings

  • 3215 Reproductive medicine
  • 1114 Paediatrics and Reproductive Medicine