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Associations between sleep duration, sleep quality and diabetic retinopathy.

Publication ,  Journal Article
Tan, NYQ; Chew, M; Tham, Y-C; Nguyen, QD; Yasuda, M; Cheng, C-Y; Wong, TY; Sabanayagam, C
Published in: PLoS One
2018

BACKGROUND: Abnormal durations of sleep have been associated with risk of diabetes. However, it is not clear if sleep duration is associated with diabetic retinopathy (DR). METHODS: In a cross-sectional study, we included 1,231 (Malay, n = 395; Indian, n = 836) adults (mean age 64.4 ± 9.0 years, 50.4% female) with diabetes from the second visit of two independent population-based cohort studies (2011-15) in Singapore. Self-reported habitual sleep duration was categorized as short (<6 h), normal (6≤ h <8), and long (≥8 h). Questionnaires were administered to detect risk of obstructive sleep apnea (OSA), excessive daytime sleepiness, and insomnia, all of which may indicate poor quality of sleep. The associations between sleep-related characteristics with moderate DR and vision-threatening DR (VTDR) were analysed using logistic regression models adjusted for potential confounders. RESULTS: Prevalence of moderate DR and VTDR in the study population were 10.5% and 6.3% respectively. The mean duration of sleep was 6.4 ± 1.5 h. Compared to normal sleep duration, both short and long sleep durations were associated with moderate DR with multivariable odds ratio (95% confidence interval) of 1.73 (1.03-2.89) and 2.17 (1.28-3.66) respectively. Long sleep duration (2.37 [1.16-4.89]), high risk of OSA (2.24 [1.09-4.75]), and excessive daytime sleepiness (3.27 [1.02-10.30]) were separately associated with VTDR. CONCLUSION: Sleep duration had a U-shaped association with moderate DR; long sleep duration, excessive daytime sleepiness and high risk of OSA were positively associated with VTDR.

Duke Scholars

Published In

PLoS One

DOI

EISSN

1932-6203

Publication Date

2018

Volume

13

Issue

5

Start / End Page

e0196399

Location

United States

Related Subject Headings

  • Surveys and Questionnaires
  • Sleep Wake Disorders
  • Sleep Apnea, Obstructive
  • Sleep
  • Singapore
  • Self Report
  • Risk Factors
  • Prevalence
  • Odds Ratio
  • Middle Aged
 

Citation

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Tan, N. Y. Q., Chew, M., Tham, Y.-C., Nguyen, Q. D., Yasuda, M., Cheng, C.-Y., … Sabanayagam, C. (2018). Associations between sleep duration, sleep quality and diabetic retinopathy. PLoS One, 13(5), e0196399. https://doi.org/10.1371/journal.pone.0196399
Tan, Nicholas Y. Q., Merwyn Chew, Yih-Chung Tham, Quang Duc Nguyen, Masayuki Yasuda, Ching-Yu Cheng, Tien Yin Wong, and Charumathi Sabanayagam. “Associations between sleep duration, sleep quality and diabetic retinopathy.PLoS One 13, no. 5 (2018): e0196399. https://doi.org/10.1371/journal.pone.0196399.
Tan NYQ, Chew M, Tham Y-C, Nguyen QD, Yasuda M, Cheng C-Y, et al. Associations between sleep duration, sleep quality and diabetic retinopathy. PLoS One. 2018;13(5):e0196399.
Tan, Nicholas Y. Q., et al. “Associations between sleep duration, sleep quality and diabetic retinopathy.PLoS One, vol. 13, no. 5, 2018, p. e0196399. Pubmed, doi:10.1371/journal.pone.0196399.
Tan NYQ, Chew M, Tham Y-C, Nguyen QD, Yasuda M, Cheng C-Y, Wong TY, Sabanayagam C. Associations between sleep duration, sleep quality and diabetic retinopathy. PLoS One. 2018;13(5):e0196399.

Published In

PLoS One

DOI

EISSN

1932-6203

Publication Date

2018

Volume

13

Issue

5

Start / End Page

e0196399

Location

United States

Related Subject Headings

  • Surveys and Questionnaires
  • Sleep Wake Disorders
  • Sleep Apnea, Obstructive
  • Sleep
  • Singapore
  • Self Report
  • Risk Factors
  • Prevalence
  • Odds Ratio
  • Middle Aged