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Quality indicators for responsible antibiotic use in the inpatient setting: a systematic review followed by an international multidisciplinary consensus procedure.

Publication ,  Journal Article
Monnier, AA; Schouten, J; Le Maréchal, M; Tebano, G; Pulcini, C; Stanic Benic, M; Vlahovic-Palcevski, V; Milanic, R; Adriaenssens, N; Huttner, B ...
Published in: J Antimicrob Chemother
June 1, 2018

BACKGROUND: This study was conducted as part of the Driving Reinvestment in Research and Development and Responsible Antibiotic Use (DRIVE-AB) project and aimed to develop generic quality indicators (QIs) for responsible antibiotic use in the inpatient setting. METHODS: A RAND-modified Delphi method was applied. First, QIs were identified by a systematic review. A complementary search was performed on web sites of relevant organizations. Duplicates were removed and disease and patient-specific QIs were combined into generic indicators. The relevance of these QIs was appraised by a multidisciplinary international stakeholder panel through two questionnaires and an in-between consensus meeting. RESULTS: The systematic review retrieved 70 potential generic QIs. The QIs were appraised by 25 international stakeholders with diverse backgrounds (medical community, public health, patients, antibiotic research and development, regulators, governments). Ultimately, 51 QIs were selected in consensus. QIs with the highest relevance score included: (i) an antibiotic plan should be documented in the medical record at the start of the antibiotic treatment; (ii) the results of bacteriological susceptibility testing should be documented in the medical record; (iii) the local guidelines should correspond to the national guidelines but should be adapted based on local resistance patterns; (iv) an antibiotic stewardship programme should be in place at the healthcare facility; and (v) allergy status should be taken into account when antibiotics are prescribed. CONCLUSIONS: This systematic and stepwise method combining evidence from literature and stakeholder opinion led to multidisciplinary international consensus on generic inpatient QIs that can be used globally to assess the quality of antibiotic use.

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Published In

J Antimicrob Chemother

DOI

EISSN

1460-2091

Publication Date

June 1, 2018

Volume

73

Issue

suppl_6

Start / End Page

vi30 / vi39

Location

England

Related Subject Headings

  • Surveys and Questionnaires
  • Stakeholder Participation
  • Quality Indicators, Health Care
  • Public Health
  • Practice Guidelines as Topic
  • Microbiology
  • Medical Records
  • Internationality
  • Inpatients
  • Humans
 

Citation

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Monnier, A. A., Schouten, J., Le Maréchal, M., Tebano, G., Pulcini, C., Stanic Benic, M., … DRIVE-AB WP1 group, . (2018). Quality indicators for responsible antibiotic use in the inpatient setting: a systematic review followed by an international multidisciplinary consensus procedure. J Antimicrob Chemother, 73(suppl_6), vi30–vi39. https://doi.org/10.1093/jac/dky116
Monnier, Annelie A., Jeroen Schouten, Marion Le Maréchal, Gianpiero Tebano, Céline Pulcini, Mirjana Stanic Benic, Vera Vlahovic-Palcevski, et al. “Quality indicators for responsible antibiotic use in the inpatient setting: a systematic review followed by an international multidisciplinary consensus procedure.J Antimicrob Chemother 73, no. suppl_6 (June 1, 2018): vi30–39. https://doi.org/10.1093/jac/dky116.
Monnier AA, Schouten J, Le Maréchal M, Tebano G, Pulcini C, Stanic Benic M, et al. Quality indicators for responsible antibiotic use in the inpatient setting: a systematic review followed by an international multidisciplinary consensus procedure. J Antimicrob Chemother. 2018 Jun 1;73(suppl_6):vi30–9.
Monnier, Annelie A., et al. “Quality indicators for responsible antibiotic use in the inpatient setting: a systematic review followed by an international multidisciplinary consensus procedure.J Antimicrob Chemother, vol. 73, no. suppl_6, June 2018, pp. vi30–39. Pubmed, doi:10.1093/jac/dky116.
Monnier AA, Schouten J, Le Maréchal M, Tebano G, Pulcini C, Stanic Benic M, Vlahovic-Palcevski V, Milanic R, Adriaenssens N, Versporten A, Huttner B, Zanichelli V, Hulscher ME, Gyssens IC, DRIVE-AB WP1 group. Quality indicators for responsible antibiotic use in the inpatient setting: a systematic review followed by an international multidisciplinary consensus procedure. J Antimicrob Chemother. 2018 Jun 1;73(suppl_6):vi30–vi39.
Journal cover image

Published In

J Antimicrob Chemother

DOI

EISSN

1460-2091

Publication Date

June 1, 2018

Volume

73

Issue

suppl_6

Start / End Page

vi30 / vi39

Location

England

Related Subject Headings

  • Surveys and Questionnaires
  • Stakeholder Participation
  • Quality Indicators, Health Care
  • Public Health
  • Practice Guidelines as Topic
  • Microbiology
  • Medical Records
  • Internationality
  • Inpatients
  • Humans