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Co-occurring reasons for medication nonadherence within subgroups of patients with hyperlipidemia.

Publication ,  Journal Article
Blalock, DV; Bosworth, HB; Reeve, BB; Voils, CI
Published in: J Behav Med
April 2019

Medication nonadherence is a significant clinical problem among individuals taking statins. Poor adherence is often attributable to several reasons, yet most adherence interventions target a single reason. Baseline data were examined from a randomized clinical trial of 236 patients with hyperlipidemia. A latent class analysis was then performed on patients reporting any nonadherence (n = 109). A 4-class solution provided the most optimal fit and differentiation of classes. Class 1 (N = 59, 54%) included patients who reported occasionally forgetting. Class 2 (N = 16, 14%) represented patients who were concerned about side effects. Class 3 (N = 17, 16%) represented patients who reported out-of-routine life events as contributing to nonadherence. Class 4 (N = 17, 16%) represented patients who endorsed a large number reasons indiscriminately. Class membership was almost uniformly unrelated to any patient demographic factors or treatment arm. Each cluster of reasons defining these patients may be best addressed through different intervention strategies.

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Published In

J Behav Med

DOI

EISSN

1573-3521

Publication Date

April 2019

Volume

42

Issue

2

Start / End Page

291 / 299

Location

United States

Related Subject Headings

  • Middle Aged
  • Medication Adherence
  • Male
  • Hyperlipidemias
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Humans
  • Female
  • Cross-Sectional Studies
  • Clinical Psychology
  • Aged
 

Citation

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Blalock, D. V., Bosworth, H. B., Reeve, B. B., & Voils, C. I. (2019). Co-occurring reasons for medication nonadherence within subgroups of patients with hyperlipidemia. J Behav Med, 42(2), 291–299. https://doi.org/10.1007/s10865-018-9954-3
Blalock, Dan V., Hayden B. Bosworth, Bryce B. Reeve, and Corrine I. Voils. “Co-occurring reasons for medication nonadherence within subgroups of patients with hyperlipidemia.J Behav Med 42, no. 2 (April 2019): 291–99. https://doi.org/10.1007/s10865-018-9954-3.
Blalock DV, Bosworth HB, Reeve BB, Voils CI. Co-occurring reasons for medication nonadherence within subgroups of patients with hyperlipidemia. J Behav Med. 2019 Apr;42(2):291–9.
Blalock, Dan V., et al. “Co-occurring reasons for medication nonadherence within subgroups of patients with hyperlipidemia.J Behav Med, vol. 42, no. 2, Apr. 2019, pp. 291–99. Pubmed, doi:10.1007/s10865-018-9954-3.
Blalock DV, Bosworth HB, Reeve BB, Voils CI. Co-occurring reasons for medication nonadherence within subgroups of patients with hyperlipidemia. J Behav Med. 2019 Apr;42(2):291–299.
Journal cover image

Published In

J Behav Med

DOI

EISSN

1573-3521

Publication Date

April 2019

Volume

42

Issue

2

Start / End Page

291 / 299

Location

United States

Related Subject Headings

  • Middle Aged
  • Medication Adherence
  • Male
  • Hyperlipidemias
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Humans
  • Female
  • Cross-Sectional Studies
  • Clinical Psychology
  • Aged