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Coronary Disease and Modifying Cardiovascular Risk in Adult Congenital Heart Disease Patients: Should General Guidelines Apply?

Publication ,  Journal Article
Awerbach, JD; Krasuski, RA; Camitta, MGW
Published in: Prog Cardiovasc Dis
2018

There are >1.4 million adult congenital heart disease (CHD; ACHD) patients living in the United States. Coronary artery disease (CAD) is at least as prevalent in ACHD patients as in the general population and has become a leading cause of their mortality. In the majority of cases, CAD in the ACHD population is driven by the presence of traditional cardiovascular disease (CVD) risk factors. 80% of ACHD patients have at least one CVD risk factor. Hypertension (HTN), obesity and physical inactivity are frequently seen in both pediatric and adult patients with CHD. Many ACHD patients demonstrate abnormal glucose metabolism and are at an increased risk for developing diabetes. Current guidelines for CVD risk assessment and prevention do not specifically mention patients with CHD but are likely applicable to most of these patients. Specific CHD populations have "high-risk" lesions that are associated with an increased risk of CVD complications and may warrant intensified screening and treatment. These include patients with a history of coarctation of the aorta or with prior coronary artery ostial manipulation (patients with a history of d-transposition of the great arteries or anomalous aortic origin of a coronary artery). The physiology of single ventricle patients is also poorly suited for the effects of superimposed CVD; these patients may benefit from intensified treatment of CVD risk factors, particularly HTN and obesity.

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Published In

Prog Cardiovasc Dis

DOI

EISSN

1873-1740

Publication Date

2018

Volume

61

Issue

3-4

Start / End Page

300 / 307

Location

United States

Related Subject Headings

  • Survivors
  • Risk Factors
  • Risk Assessment
  • Preventive Health Services
  • Prevalence
  • Practice Guidelines as Topic
  • Humans
  • Heart Defects, Congenital
  • Cardiovascular System & Hematology
  • Cardiovascular Diseases
 

Citation

APA
Chicago
ICMJE
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Awerbach, J. D., Krasuski, R. A., & Camitta, M. G. W. (2018). Coronary Disease and Modifying Cardiovascular Risk in Adult Congenital Heart Disease Patients: Should General Guidelines Apply? Prog Cardiovasc Dis, 61(3–4), 300–307. https://doi.org/10.1016/j.pcad.2018.07.018
Awerbach, Jordan D., Richard A. Krasuski, and Michael G. W. Camitta. “Coronary Disease and Modifying Cardiovascular Risk in Adult Congenital Heart Disease Patients: Should General Guidelines Apply?Prog Cardiovasc Dis 61, no. 3–4 (2018): 300–307. https://doi.org/10.1016/j.pcad.2018.07.018.
Awerbach, Jordan D., et al. “Coronary Disease and Modifying Cardiovascular Risk in Adult Congenital Heart Disease Patients: Should General Guidelines Apply?Prog Cardiovasc Dis, vol. 61, no. 3–4, 2018, pp. 300–07. Pubmed, doi:10.1016/j.pcad.2018.07.018.
Awerbach JD, Krasuski RA, Camitta MGW. Coronary Disease and Modifying Cardiovascular Risk in Adult Congenital Heart Disease Patients: Should General Guidelines Apply? Prog Cardiovasc Dis. 2018;61(3–4):300–307.
Journal cover image

Published In

Prog Cardiovasc Dis

DOI

EISSN

1873-1740

Publication Date

2018

Volume

61

Issue

3-4

Start / End Page

300 / 307

Location

United States

Related Subject Headings

  • Survivors
  • Risk Factors
  • Risk Assessment
  • Preventive Health Services
  • Prevalence
  • Practice Guidelines as Topic
  • Humans
  • Heart Defects, Congenital
  • Cardiovascular System & Hematology
  • Cardiovascular Diseases