Transperitoneal Versus Extraperitoneal Laparoscopic Lymphadenectomy for Gynecological Malignancies: A Systematic Review and Meta-analysis.
Para-aortic lymphadenectomy is established as a standard procedure for disease staging and management of patients with advanced cervical, ovarian and high-risk endometrial cancer. Our meta-analysis accumulated the current evidence on the impact of transperitoneal (TLL) and extraperitoneal (ELL) laparoscopic lymphadenectomy for the management of patients with gynecological malignancies.A systematic search of the literature was undertaken for articles published up to April 2018. Statistical meta-analysis was performed using the RevMan 5.3 software.Seven studies were eligible for meta-analysis and comprised a total of 608 women. ELL was associated with significantly shorter operative times for lymphadenectomy, whereas total operative times were not different between the two groups. Significantly increased intraoperative complications were found in the TLL group.ELL is safe and efficient with outcomes comparable to TLL in terms of lymph node yield and improved operative outcomes with regard to lymphadenectomy times and intraoperative complications.
Duke Scholars
Published In
DOI
EISSN
ISSN
Publication Date
Volume
Issue
Start / End Page
Related Subject Headings
- Uterine Cervical Neoplasms
- Retrospective Studies
- Prospective Studies
- Ovarian Neoplasms
- Oncology & Carcinogenesis
- Neoplasm Staging
- Lymphatic Metastasis
- Lymph Nodes
- Lymph Node Excision
- Laparoscopy
Citation
Published In
DOI
EISSN
ISSN
Publication Date
Volume
Issue
Start / End Page
Related Subject Headings
- Uterine Cervical Neoplasms
- Retrospective Studies
- Prospective Studies
- Ovarian Neoplasms
- Oncology & Carcinogenesis
- Neoplasm Staging
- Lymphatic Metastasis
- Lymph Nodes
- Lymph Node Excision
- Laparoscopy