Scholars@Duke

A-102 Antibody binding to HIV-1 infected cells as mechanism for treatment of HIV infection

Publication ,  Conference
Ferrari, G; Nordstrom, J; Koenig, S; Sung, J; Margolis, D; Haynes, B
Published in: JAIDS Journal of Acquired Immune Deficiency Syndromes
April 2018
Published version (DOI) Publisher Link

Anti-HIV antibody function is not limited to capturing free virus but also includes the recognition of HIV-1 infected cells. Both neutralizing and nonneutralizing antibody responses recognizing HIV-1 envelope epitopes expressed on the cellular membrane can recruit Fc receptor-bearing cells and direct their cytotoxic activity against the infected cells. We can leverage on our ability to use monoclonal antibody and monoclonal antibody-based molecules to protect from and treat HIV-1 infection.

Duke Scholars

Guido Ferrari
Author Guido Ferrari Surgery, Surgical Sciences
Barton Ford Haynes
Author Barton Ford Haynes Medicine, Duke Human Vaccine Institute

Published In

JAIDS Journal of Acquired Immune Deficiency Syndromes

DOI

10.1097/01.qai.0000532483.69631.d6

ISSN

1525-4135

Publication Date

April 2018

Volume

77

Issue

1

Start / End Page

33 / 33

Publisher

Ovid Technologies (Wolters Kluwer Health)

Related Subject Headings

  • Virology
  • 4206 Public health
  • 4202 Epidemiology
  • 3202 Clinical sciences
  • 1117 Public Health and Health Services
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Ferrari, G., Nordstrom, J., Koenig, S., Sung, J., Margolis, D., & Haynes, B. (2018). A-102 Antibody binding to HIV-1 infected cells as mechanism for treatment of HIV infection. In JAIDS Journal of Acquired Immune Deficiency Syndromes (Vol. 77, pp. 33–33). Ovid Technologies (Wolters Kluwer Health). https://doi.org/10.1097/01.qai.0000532483.69631.d6
Ferrari, Guido, Jeffrey Nordstrom, Scott Koenig, Julia Sung, David Margolis, and Barton Haynes. “A-102 Antibody binding to HIV-1 infected cells as mechanism for treatment of HIV infection.” In JAIDS Journal of Acquired Immune Deficiency Syndromes, 77:33–33. Ovid Technologies (Wolters Kluwer Health), 2018. https://doi.org/10.1097/01.qai.0000532483.69631.d6.
Ferrari G, Nordstrom J, Koenig S, Sung J, Margolis D, Haynes B. A-102 Antibody binding to HIV-1 infected cells as mechanism for treatment of HIV infection. In: JAIDS Journal of Acquired Immune Deficiency Syndromes. Ovid Technologies (Wolters Kluwer Health); 2018. p. 33–33.
Ferrari, Guido, et al. “A-102 Antibody binding to HIV-1 infected cells as mechanism for treatment of HIV infection.” JAIDS Journal of Acquired Immune Deficiency Syndromes, vol. 77, no. 1, Ovid Technologies (Wolters Kluwer Health), 2018, pp. 33–33. Crossref, doi:10.1097/01.qai.0000532483.69631.d6.
Ferrari G, Nordstrom J, Koenig S, Sung J, Margolis D, Haynes B. A-102 Antibody binding to HIV-1 infected cells as mechanism for treatment of HIV infection. JAIDS Journal of Acquired Immune Deficiency Syndromes. Ovid Technologies (Wolters Kluwer Health); 2018. p. 33–33.

Published In

JAIDS Journal of Acquired Immune Deficiency Syndromes

DOI

10.1097/01.qai.0000532483.69631.d6

ISSN

1525-4135

Publication Date

April 2018

Volume

77

Issue

1

Start / End Page

33 / 33

Publisher

Ovid Technologies (Wolters Kluwer Health)

Related Subject Headings

  • Virology
  • 4206 Public health
  • 4202 Epidemiology
  • 3202 Clinical sciences
  • 1117 Public Health and Health Services
  • 1103 Clinical Sciences