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Neurosurgical applications of fibrin glue: augmentation of dural closure in 134 patients.

Publication ,  Journal Article
Shaffrey, CI; Spotnitz, WD; Shaffrey, ME; Jane, JA
Published in: Neurosurgery
February 1990

In a wide variety of neurosurgical procedures performed on 134 patients over a 3-year period, fibrin glue has been applied as an adjunct to dural closure. Overall success at preventing cerebrospinal fluid (CSF) leakage was 90% (121 of 134, 90% effective). In patients considered to be at high risk for CSF leakage intraoperatively but without pre-established fistulae (Group 1), the success rate was higher (111 of 119, 93% effective). In patients with pre-established CSF fistulae (Group 2), the success rate was lower (10 of 15, 67% effective). As single donor sources of concentrated fibrinogen are now available with reduced risks of blood-borne disease transmission, fibrin glue may be a valuable clinical tool for the neurosurgeon.

Duke Scholars

Published In

Neurosurgery

ISSN

0148-396X

Publication Date

February 1990

Volume

26

Issue

2

Start / End Page

207 / 210

Location

United States

Related Subject Headings

  • Retrospective Studies
  • Neurosurgery
  • Neurology & Neurosurgery
  • Humans
  • Fibrin Tissue Adhesive
  • Dura Mater
  • 5202 Biological psychology
  • 3209 Neurosciences
  • 3202 Clinical sciences
  • 1109 Neurosciences
 

Citation

APA
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ICMJE
MLA
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Shaffrey, C. I., Spotnitz, W. D., Shaffrey, M. E., & Jane, J. A. (1990). Neurosurgical applications of fibrin glue: augmentation of dural closure in 134 patients. Neurosurgery, 26(2), 207–210.
Shaffrey, C. I., W. D. Spotnitz, M. E. Shaffrey, and J. A. Jane. “Neurosurgical applications of fibrin glue: augmentation of dural closure in 134 patients.Neurosurgery 26, no. 2 (February 1990): 207–10.
Shaffrey CI, Spotnitz WD, Shaffrey ME, Jane JA. Neurosurgical applications of fibrin glue: augmentation of dural closure in 134 patients. Neurosurgery. 1990 Feb;26(2):207–10.
Shaffrey, C. I., et al. “Neurosurgical applications of fibrin glue: augmentation of dural closure in 134 patients.Neurosurgery, vol. 26, no. 2, Feb. 1990, pp. 207–10.
Shaffrey CI, Spotnitz WD, Shaffrey ME, Jane JA. Neurosurgical applications of fibrin glue: augmentation of dural closure in 134 patients. Neurosurgery. 1990 Feb;26(2):207–210.
Journal cover image

Published In

Neurosurgery

ISSN

0148-396X

Publication Date

February 1990

Volume

26

Issue

2

Start / End Page

207 / 210

Location

United States

Related Subject Headings

  • Retrospective Studies
  • Neurosurgery
  • Neurology & Neurosurgery
  • Humans
  • Fibrin Tissue Adhesive
  • Dura Mater
  • 5202 Biological psychology
  • 3209 Neurosciences
  • 3202 Clinical sciences
  • 1109 Neurosciences