Pathogenesis of varicose veins.
Publication
, Journal Article
Oklu, R; Habito, R; Mayr, M; Deipolyi, AR; Albadawi, H; Hesketh, R; Walker, TG; Linskey, KR; Long, CA; Wicky, S; Stoughton, J; Watkins, MT
Published in: J Vasc Interv Radiol
January 2012
Despite the high prevalence of varicose veins and the recent surge in research on the condition, the precise mechanisms underlying their development remain uncertain. In the past decade, there has been a shift from initial theories based on purely mechanical factors to hypotheses pointing to complex molecular changes causing histologic alterations in the vessel wall and extracellular matrix. Despite progress in understanding the molecular aspects of venous insufficiency, therapies for symptomatic varicose veins are directed toward anatomic and physical interventions. The present report reviews current evidence identifying the underlying biochemical alterations in the pathogenesis of varicose veins.
Duke Scholars
Published In
J Vasc Interv Radiol
DOI
EISSN
1535-7732
Publication Date
January 2012
Volume
23
Issue
1
Start / End Page
33 / 39
Location
United States
Related Subject Headings
- Varicose Veins
- Transforming Growth Factor beta
- Risk Factors
- Nuclear Medicine & Medical Imaging
- Muscle, Smooth, Vascular
- Humans
- Genomics
- Genetic Predisposition to Disease
- Biomarkers
- 3202 Clinical sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Oklu, R., Habito, R., Mayr, M., Deipolyi, A. R., Albadawi, H., Hesketh, R., … Watkins, M. T. (2012). Pathogenesis of varicose veins. J Vasc Interv Radiol, 23(1), 33–39. https://doi.org/10.1016/j.jvir.2011.09.010
Oklu, Rahmi, Roy Habito, Manuel Mayr, Amy R. Deipolyi, Hassan Albadawi, Robin Hesketh, T Gregory Walker, et al. “Pathogenesis of varicose veins.” J Vasc Interv Radiol 23, no. 1 (January 2012): 33–39. https://doi.org/10.1016/j.jvir.2011.09.010.
Oklu R, Habito R, Mayr M, Deipolyi AR, Albadawi H, Hesketh R, et al. Pathogenesis of varicose veins. J Vasc Interv Radiol. 2012 Jan;23(1):33–9.
Oklu, Rahmi, et al. “Pathogenesis of varicose veins.” J Vasc Interv Radiol, vol. 23, no. 1, Jan. 2012, pp. 33–39. Pubmed, doi:10.1016/j.jvir.2011.09.010.
Oklu R, Habito R, Mayr M, Deipolyi AR, Albadawi H, Hesketh R, Walker TG, Linskey KR, Long CA, Wicky S, Stoughton J, Watkins MT. Pathogenesis of varicose veins. J Vasc Interv Radiol. 2012 Jan;23(1):33–39.
Published In
J Vasc Interv Radiol
DOI
EISSN
1535-7732
Publication Date
January 2012
Volume
23
Issue
1
Start / End Page
33 / 39
Location
United States
Related Subject Headings
- Varicose Veins
- Transforming Growth Factor beta
- Risk Factors
- Nuclear Medicine & Medical Imaging
- Muscle, Smooth, Vascular
- Humans
- Genomics
- Genetic Predisposition to Disease
- Biomarkers
- 3202 Clinical sciences