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Present status of pyoderma gangrenosum. Review of 21 cases.

Publication ,  Journal Article
Prystowsky, JH; Kahn, SN; Lazarus, GS
Published in: Arch Dermatol
January 1989

This article summarizes the management of 22 cases of pyoderma gangrenosum over the past four years at the hospital of the University of Pennsylvania, Philadelphia. Eighteen patients with pyoderma gangrenosum were studied using the most sensitive routine laboratory method for detection of monoclonal immunoglobulins, immunofixation electrophoresis. Four cases of IgA gammopathy were detected, confirming previous reports of the incidence of monoclonal gammopathy in pyoderma gangrenosum. High-dose glucocorticoid therapy (pulse therapy) is an effective treatment for some severe, refractory cases of pyoderma gangrenosum. Eight patients were treated with pulse therapy. Six responded favorably, and none had serious complications.

Duke Scholars

Published In

Arch Dermatol

ISSN

0003-987X

Publication Date

January 1989

Volume

125

Issue

1

Start / End Page

57 / 64

Location

United States

Related Subject Headings

  • Skin Ulcer
  • Pyoderma
  • Monoclonal Gammopathy of Undetermined Significance
  • Middle Aged
  • Male
  • Immunoglobulin A
  • Immunoelectrophoresis
  • Humans
  • Female
  • Dermatology & Venereal Diseases
 

Citation

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MLA
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Prystowsky, J. H., Kahn, S. N., & Lazarus, G. S. (1989). Present status of pyoderma gangrenosum. Review of 21 cases. Arch Dermatol, 125(1), 57–64.
Prystowsky, J. H., S. N. Kahn, and G. S. Lazarus. “Present status of pyoderma gangrenosum. Review of 21 cases.Arch Dermatol 125, no. 1 (January 1989): 57–64.
Prystowsky JH, Kahn SN, Lazarus GS. Present status of pyoderma gangrenosum. Review of 21 cases. Arch Dermatol. 1989 Jan;125(1):57–64.
Prystowsky, J. H., et al. “Present status of pyoderma gangrenosum. Review of 21 cases.Arch Dermatol, vol. 125, no. 1, Jan. 1989, pp. 57–64.
Prystowsky JH, Kahn SN, Lazarus GS. Present status of pyoderma gangrenosum. Review of 21 cases. Arch Dermatol. 1989 Jan;125(1):57–64.

Published In

Arch Dermatol

ISSN

0003-987X

Publication Date

January 1989

Volume

125

Issue

1

Start / End Page

57 / 64

Location

United States

Related Subject Headings

  • Skin Ulcer
  • Pyoderma
  • Monoclonal Gammopathy of Undetermined Significance
  • Middle Aged
  • Male
  • Immunoglobulin A
  • Immunoelectrophoresis
  • Humans
  • Female
  • Dermatology & Venereal Diseases