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Meeting report of the STAR-Sensitization in Transplantation Assessment of Risk: Naïve Abdominal Transplant Organ subgroup focus on kidney transplantation.

Publication ,  Journal Article
Mannon, RB; Askar, M; Jackson, AM; Newell, K; Mengel, M
Published in: Am J Transplant
September 2018

The development of de novo donor-specific HLA antibody (dnDSA) is a critical feature contributing to late allograft failure. The complexity of the issue is further complicated by organ-specific differences, detection techniques, reliance of tissue histopathology and changing diagnostic criteria, ineffective therapies, and lack of consensus. To tackle these issues, the Sensitization in Transplantation Assessment of Risk (STAR) 2017 was initiated as a collaboration of the American Society of Transplantation and American Society of Histocompatibility and Immunogenetics consisting of 8 working groups with the goal to provide guidelines on how to assess risk and risk stratify patients based on their potential alloimmune and DSA status. Herein is a summary of discussions by the Naïve Abdominal Working Group, highlighting currently available data and identifying gaps in our knowledge on the development and impact of dnDSA following kidney transplantation.

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Published In

Am J Transplant

DOI

EISSN

1600-6143

Publication Date

September 2018

Volume

18

Issue

9

Start / End Page

2120 / 2134

Location

United States

Related Subject Headings

  • Tissue Donors
  • Surgery
  • Societies, Medical
  • Risk Assessment
  • Research Report
  • Kidney Transplantation
  • Isoantibodies
  • Humans
  • Histocompatibility
  • HLA Antigens
 

Citation

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Mannon, R. B., Askar, M., Jackson, A. M., Newell, K., & Mengel, M. (2018). Meeting report of the STAR-Sensitization in Transplantation Assessment of Risk: Naïve Abdominal Transplant Organ subgroup focus on kidney transplantation. Am J Transplant, 18(9), 2120–2134. https://doi.org/10.1111/ajt.14977
Mannon, Roslyn B., Medhat Askar, Annette M. Jackson, Kenneth Newell, and Michael Mengel. “Meeting report of the STAR-Sensitization in Transplantation Assessment of Risk: Naïve Abdominal Transplant Organ subgroup focus on kidney transplantation.Am J Transplant 18, no. 9 (September 2018): 2120–34. https://doi.org/10.1111/ajt.14977.
Mannon, Roslyn B., et al. “Meeting report of the STAR-Sensitization in Transplantation Assessment of Risk: Naïve Abdominal Transplant Organ subgroup focus on kidney transplantation.Am J Transplant, vol. 18, no. 9, Sept. 2018, pp. 2120–34. Pubmed, doi:10.1111/ajt.14977.
Journal cover image

Published In

Am J Transplant

DOI

EISSN

1600-6143

Publication Date

September 2018

Volume

18

Issue

9

Start / End Page

2120 / 2134

Location

United States

Related Subject Headings

  • Tissue Donors
  • Surgery
  • Societies, Medical
  • Risk Assessment
  • Research Report
  • Kidney Transplantation
  • Isoantibodies
  • Humans
  • Histocompatibility
  • HLA Antigens