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Sensing Mitochondrial Acetyl-CoA to Tune Respiration.

Publication ,  Journal Article
Mills, CA; Trub, AG; Hirschey, MD
Published in: Trends Endocrinol Metab
January 2019

Fatty acid synthesis (FAS) in mitochondria produces a key metabolite called lipoic acid. However, a new study by Van Vranken et al.[1] (Mol. Cell 2018;71:567-580) shows that mitochondrial FAS regulates the assembly of oxidative phosphorylation complexes, thereby functioning as a nutrient sensor for mitochondrial respiration.

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Published In

Trends Endocrinol Metab

DOI

EISSN

1879-3061

Publication Date

January 2019

Volume

30

Issue

1

Start / End Page

1 / 3

Location

United States

Related Subject Headings

  • Respiration
  • Mitochondria
  • Fatty Acids
  • Eukaryota
  • Endocrinology & Metabolism
  • Acyl Carrier Protein
  • Acetyl Coenzyme A
  • 3215 Reproductive medicine
  • 1114 Paediatrics and Reproductive Medicine
  • 1103 Clinical Sciences
 

Citation

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Chicago
ICMJE
MLA
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Mills, C. A., Trub, A. G., & Hirschey, M. D. (2019). Sensing Mitochondrial Acetyl-CoA to Tune Respiration. Trends Endocrinol Metab, 30(1), 1–3. https://doi.org/10.1016/j.tem.2018.10.003
Mills, Christine A., Alec G. Trub, and Matthew D. Hirschey. “Sensing Mitochondrial Acetyl-CoA to Tune Respiration.Trends Endocrinol Metab 30, no. 1 (January 2019): 1–3. https://doi.org/10.1016/j.tem.2018.10.003.
Mills CA, Trub AG, Hirschey MD. Sensing Mitochondrial Acetyl-CoA to Tune Respiration. Trends Endocrinol Metab. 2019 Jan;30(1):1–3.
Mills, Christine A., et al. “Sensing Mitochondrial Acetyl-CoA to Tune Respiration.Trends Endocrinol Metab, vol. 30, no. 1, Jan. 2019, pp. 1–3. Pubmed, doi:10.1016/j.tem.2018.10.003.
Mills CA, Trub AG, Hirschey MD. Sensing Mitochondrial Acetyl-CoA to Tune Respiration. Trends Endocrinol Metab. 2019 Jan;30(1):1–3.
Journal cover image

Published In

Trends Endocrinol Metab

DOI

EISSN

1879-3061

Publication Date

January 2019

Volume

30

Issue

1

Start / End Page

1 / 3

Location

United States

Related Subject Headings

  • Respiration
  • Mitochondria
  • Fatty Acids
  • Eukaryota
  • Endocrinology & Metabolism
  • Acyl Carrier Protein
  • Acetyl Coenzyme A
  • 3215 Reproductive medicine
  • 1114 Paediatrics and Reproductive Medicine
  • 1103 Clinical Sciences