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Modern Neurosurgery: Clinical Translation of Neuroscience Advances

Novel therapeutic approaches for high-grade gliomas

Publication ,  Chapter
New, KC; Adamson, DC; Selznick, L; Sampson, J
January 1, 2004

The incidence of primary brain tumors is increasing. Approximately 18,000 new cases were expected in the U.S. in 2003.1 High-grade gliomas (HGGs) including glioblastoma multiforme (GBM) and anaplastic astrocytoma (AA) are the most common primary tumors of the central nervous system (CNS). HGGs remain refractory to treatment and have dismal prognoses. The median survival for AA patients is approximately 2 years, the median is 9 months for GBM patients.2 Neurosurgeons remain intimately involved in the care of patients with HGG and with research into new treatments for this deadly disease. This stems in part from the fact that surgical resection continues to be an important treatment for HGG.

Duke Scholars

ISBN

9780849314827

Publication Date

January 1, 2004

Start / End Page

159 / 184
 

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New, K. C., Adamson, D. C., Selznick, L., & Sampson, J. (2004). Novel therapeutic approaches for high-grade gliomas. In Modern Neurosurgery: Clinical Translation of Neuroscience Advances (pp. 159–184).
New, K. C., D. C. Adamson, L. Selznick, and J. Sampson. “Novel therapeutic approaches for high-grade gliomas.” In Modern Neurosurgery: Clinical Translation of Neuroscience Advances, 159–84, 2004.
New KC, Adamson DC, Selznick L, Sampson J. Novel therapeutic approaches for high-grade gliomas. In: Modern Neurosurgery: Clinical Translation of Neuroscience Advances. 2004. p. 159–84.
New, K. C., et al. “Novel therapeutic approaches for high-grade gliomas.” Modern Neurosurgery: Clinical Translation of Neuroscience Advances, 2004, pp. 159–84.
New KC, Adamson DC, Selznick L, Sampson J. Novel therapeutic approaches for high-grade gliomas. Modern Neurosurgery: Clinical Translation of Neuroscience Advances. 2004. p. 159–184.
Journal cover image

ISBN

9780849314827

Publication Date

January 1, 2004

Start / End Page

159 / 184