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Assessment of rates of structural change in glaucoma using imaging technologies

Publication ,  Journal Article
Mansouri, K; Leite, MT; Medeiros, FA; Leung, CK; Weinreb, RN
Published in: Eye
January 1, 2011

Purpose To review the ability of current imaging technologies to provide estimates of rates of structural change in glaucoma patients.Patients and methodsReview of literature.ResultsImaging technologies, such as confocal scanning laser ophthalmoscopy (CSLO), scanning laser polarimetry (SLP), and optical coherence tomography (OCT), provide quantifiable and reproducible measurements of the optic disc and parapapillary retinal nerve fibre layer (RNFL). Rates of change as quantified by the rim area (RA) (for CSLO) and RNFL thickness (for SLP and OCT) are related to glaucoma progression as detected by conventional methods (eg, visual fields and optic disc photography). Evidence shows that rates of RNFL and RA loss are significantly faster in progressing compared with non-progressing glaucoma patients.ConclusionMeasurements of rates of optic disc and RNFL change are becoming increasingly precise and individualized. Currently available imaging technologies have the ability to detect and quantify progression in glaucoma, and their measurements may be suitable end points in glaucoma clinical trials. © 2011 Macmillan Publishers Limited All rights reserved.

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Published In

Eye

DOI

EISSN

1476-5454

ISSN

0950-222X

Publication Date

January 1, 2011

Volume

25

Issue

3

Start / End Page

269 / 277

Related Subject Headings

  • Ophthalmology & Optometry
  • 3212 Ophthalmology and optometry
  • 3204 Immunology
  • 1113 Opthalmology and Optometry
  • 1107 Immunology
  • 1103 Clinical Sciences
 

Citation

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Chicago
ICMJE
MLA
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Mansouri, K., Leite, M. T., Medeiros, F. A., Leung, C. K., & Weinreb, R. N. (2011). Assessment of rates of structural change in glaucoma using imaging technologies. Eye, 25(3), 269–277. https://doi.org/10.1038/eye.2010.202
Mansouri, K., M. T. Leite, F. A. Medeiros, C. K. Leung, and R. N. Weinreb. “Assessment of rates of structural change in glaucoma using imaging technologies.” Eye 25, no. 3 (January 1, 2011): 269–77. https://doi.org/10.1038/eye.2010.202.
Mansouri K, Leite MT, Medeiros FA, Leung CK, Weinreb RN. Assessment of rates of structural change in glaucoma using imaging technologies. Eye. 2011 Jan 1;25(3):269–77.
Mansouri, K., et al. “Assessment of rates of structural change in glaucoma using imaging technologies.” Eye, vol. 25, no. 3, Jan. 2011, pp. 269–77. Scopus, doi:10.1038/eye.2010.202.
Mansouri K, Leite MT, Medeiros FA, Leung CK, Weinreb RN. Assessment of rates of structural change in glaucoma using imaging technologies. Eye. 2011 Jan 1;25(3):269–277.

Published In

Eye

DOI

EISSN

1476-5454

ISSN

0950-222X

Publication Date

January 1, 2011

Volume

25

Issue

3

Start / End Page

269 / 277

Related Subject Headings

  • Ophthalmology & Optometry
  • 3212 Ophthalmology and optometry
  • 3204 Immunology
  • 1113 Opthalmology and Optometry
  • 1107 Immunology
  • 1103 Clinical Sciences