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The effect of intraocular irrigating solutions on lens clarity in normal and diabetic rabbits.

Publication ,  Journal Article
Haimann, MH; Abrams, GW; Edelhauser, HF; Hatchell, DL
Published in: Am J Ophthalmol
November 1982

We conducted a series of experiments on normal and diabetic rabbits to evaluate the effect of intraocular irrigating solutions on the lens. Lenticular clarity was studied in vivo in eyes undergoing vitreous cavity perfusions with various irrigating solutions. The clarity of isolated lenses incubated in these same solutions was also evaluated. In order to quantitate the cataractous changes observed, we measured the uptake of inulin (tagged with radioactive carbon) by isolated lenses. We found that balanced salt solution (BSS) and BSS Plus maintain excellent lens clarity in normal rabbits; that diabetic lenses are more likely to develop opacification than normal lenses, becoming cataractous when exposed to BSS Plus; and that adding supplemental glucose to BSS Plus allows this solution to maintain excellent lens clarity in diabetic rabbits.

Duke Scholars

Published In

Am J Ophthalmol

DOI

ISSN

0002-9394

Publication Date

November 1982

Volume

94

Issue

5

Start / End Page

594 / 605

Location

United States

Related Subject Headings

  • Vitreous Body
  • Therapeutic Irrigation
  • Sodium Chloride
  • Rabbits
  • Ophthalmology & Optometry
  • Ophthalmic Solutions
  • Lens, Crystalline
  • Intraocular Pressure
  • Insulin
  • In Vitro Techniques
 

Citation

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Haimann, M. H., Abrams, G. W., Edelhauser, H. F., & Hatchell, D. L. (1982). The effect of intraocular irrigating solutions on lens clarity in normal and diabetic rabbits. Am J Ophthalmol, 94(5), 594–605. https://doi.org/10.1016/0002-9394(82)90003-4
Haimann, M. H., G. W. Abrams, H. F. Edelhauser, and D. L. Hatchell. “The effect of intraocular irrigating solutions on lens clarity in normal and diabetic rabbits.Am J Ophthalmol 94, no. 5 (November 1982): 594–605. https://doi.org/10.1016/0002-9394(82)90003-4.
Haimann MH, Abrams GW, Edelhauser HF, Hatchell DL. The effect of intraocular irrigating solutions on lens clarity in normal and diabetic rabbits. Am J Ophthalmol. 1982 Nov;94(5):594–605.
Haimann, M. H., et al. “The effect of intraocular irrigating solutions on lens clarity in normal and diabetic rabbits.Am J Ophthalmol, vol. 94, no. 5, Nov. 1982, pp. 594–605. Pubmed, doi:10.1016/0002-9394(82)90003-4.
Haimann MH, Abrams GW, Edelhauser HF, Hatchell DL. The effect of intraocular irrigating solutions on lens clarity in normal and diabetic rabbits. Am J Ophthalmol. 1982 Nov;94(5):594–605.
Journal cover image

Published In

Am J Ophthalmol

DOI

ISSN

0002-9394

Publication Date

November 1982

Volume

94

Issue

5

Start / End Page

594 / 605

Location

United States

Related Subject Headings

  • Vitreous Body
  • Therapeutic Irrigation
  • Sodium Chloride
  • Rabbits
  • Ophthalmology & Optometry
  • Ophthalmic Solutions
  • Lens, Crystalline
  • Intraocular Pressure
  • Insulin
  • In Vitro Techniques