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High-Pitch Wide-Coverage Fast-Kilovoltage-Switching Dual-Energy CT: Impact of Pitch on Noise, Spatial Resolution, and Iodine Quantification in a Phantom Study.

Publication ,  Journal Article
Euler, A; Solomon, J; Farjat, AE; Nelson, RC; Samei, E; Marin, D
Published in: AJR Am J Roentgenol
March 2019

OBJECTIVE: The purpose of this study was to assess the impact of high pitch values on image noise, spatial resolution, and iodine quantification in single-source wide-coverage fast-kilovoltage-switching dual-energy CT (DECT). MATERIALS AND METHODS: Two phantom experiments were conducted. First, image noise and spatial resolution in the x-, y-, and z-directions were assessed. Second, the accuracy of iodine quantification was investigated with multiple-size phantoms with pure iodine and blood-iodine inserts. Both phantoms were scanned repeatedly with a third-generation fast-kilovoltage-switching DECT scanner with a collimation width of 80 mm at four different pitch values (0.5, 0.99, 1.375, 1.53) and three different gantry rotation times (0.6, 0.8, 1.0 second). Image noise, spatial resolution, and absolute error of iodine concentration (E) were measured. A linear mixed effects model was used to determine the effect of pitch, rotation time, and size on the error of iodine concentration. RESULTS: Image noise and xy spatial resolution were comparable among the four pitch values. Spatial resolution in the z-direction was inferior and had higher variance at a low pitch of 0.5 compared with pitches of 0.99, 1.375, and 1.53. Error of iodine concentration was significantly affected by pitch and rotation time (p < 0.001). E decreased with increasing pitch and decreasing rotation time. In detail, mean E was 0.91 ± 0.47 mg I/mL for a pitch of 0.5, 0.52 ± 0.29 mg I/mL for 0.99, 0.44 ± 0.25 mg I/mL for 1.375, and 0.40 ± 0.25 mg I/mL for 1.53. CONCLUSION: High-pitch wide-coverage fast-kilovoltage-switching DECT can be performed without impairing image quality or iodine quantification, and the results are superior to those of imaging at a low pitch of 0.5.

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Published In

AJR Am J Roentgenol

DOI

EISSN

1546-3141

Publication Date

March 2019

Volume

212

Issue

3

Start / End Page

W64 / W72

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Tomography Scanners, X-Ray Computed
  • Phantoms, Imaging
  • Nuclear Medicine & Medical Imaging
  • Iodine
  • Humans
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

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ICMJE
MLA
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Euler, A., Solomon, J., Farjat, A. E., Nelson, R. C., Samei, E., & Marin, D. (2019). High-Pitch Wide-Coverage Fast-Kilovoltage-Switching Dual-Energy CT: Impact of Pitch on Noise, Spatial Resolution, and Iodine Quantification in a Phantom Study. AJR Am J Roentgenol, 212(3), W64–W72. https://doi.org/10.2214/AJR.18.19851
Euler, André, Justin Solomon, Alfredo E. Farjat, Rendon C. Nelson, Ehsan Samei, and Daniele Marin. “High-Pitch Wide-Coverage Fast-Kilovoltage-Switching Dual-Energy CT: Impact of Pitch on Noise, Spatial Resolution, and Iodine Quantification in a Phantom Study.AJR Am J Roentgenol 212, no. 3 (March 2019): W64–72. https://doi.org/10.2214/AJR.18.19851.
Euler A, Solomon J, Farjat AE, Nelson RC, Samei E, Marin D. High-Pitch Wide-Coverage Fast-Kilovoltage-Switching Dual-Energy CT: Impact of Pitch on Noise, Spatial Resolution, and Iodine Quantification in a Phantom Study. AJR Am J Roentgenol. 2019 Mar;212(3):W64–72.
Euler, André, et al. “High-Pitch Wide-Coverage Fast-Kilovoltage-Switching Dual-Energy CT: Impact of Pitch on Noise, Spatial Resolution, and Iodine Quantification in a Phantom Study.AJR Am J Roentgenol, vol. 212, no. 3, Mar. 2019, pp. W64–72. Pubmed, doi:10.2214/AJR.18.19851.
Euler A, Solomon J, Farjat AE, Nelson RC, Samei E, Marin D. High-Pitch Wide-Coverage Fast-Kilovoltage-Switching Dual-Energy CT: Impact of Pitch on Noise, Spatial Resolution, and Iodine Quantification in a Phantom Study. AJR Am J Roentgenol. 2019 Mar;212(3):W64–W72.

Published In

AJR Am J Roentgenol

DOI

EISSN

1546-3141

Publication Date

March 2019

Volume

212

Issue

3

Start / End Page

W64 / W72

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Tomography Scanners, X-Ray Computed
  • Phantoms, Imaging
  • Nuclear Medicine & Medical Imaging
  • Iodine
  • Humans
  • 3202 Clinical sciences
  • 1103 Clinical Sciences