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The promise of immunotherapy in genitourinary malignancies.

Publication ,  Journal Article
Zhang, T; Armstrong, AJ; George, DJ; Huang, J
Published in: Precis Clin Med
December 2018

A broad understanding of the tumor immune landscape has led to a revolution of immune checkpoint inhibitors in the treatment of multiple cancer types. In genitourinary malignancies, immune checkpoint inhibitors have improved outcomes for patients with metastatic renal cell carcinoma and metastatic urothelial carcinoma; however, these treatments have not yet proven broadly beneficial for patients with metastatic prostate cancer. Numerous prospective trials are ongoing to further improve outcomes with immunotherapy combinations and for biomarker development to predict benefit from immune checkpoint inhibition. This perspective article highlights our current immunotherapy approaches in each of the genitourinary malignancies and the ongoing clinical trials that may inform our future treatments in renal, urothelial, and prostate cancers.

Duke Scholars

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Published In

Precis Clin Med

DOI

EISSN

2516-1571

Publication Date

December 2018

Volume

1

Issue

3

Start / End Page

97 / 101

Location

England
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Zhang, T., Armstrong, A. J., George, D. J., & Huang, J. (2018). The promise of immunotherapy in genitourinary malignancies. Precis Clin Med, 1(3), 97–101. https://doi.org/10.1093/pcmedi/pby018
Zhang, Tian, Andrew J. Armstrong, Daniel J. George, and Jiaoti Huang. “The promise of immunotherapy in genitourinary malignancies.Precis Clin Med 1, no. 3 (December 2018): 97–101. https://doi.org/10.1093/pcmedi/pby018.
Zhang T, Armstrong AJ, George DJ, Huang J. The promise of immunotherapy in genitourinary malignancies. Precis Clin Med. 2018 Dec;1(3):97–101.
Zhang, Tian, et al. “The promise of immunotherapy in genitourinary malignancies.Precis Clin Med, vol. 1, no. 3, Dec. 2018, pp. 97–101. Pubmed, doi:10.1093/pcmedi/pby018.
Zhang T, Armstrong AJ, George DJ, Huang J. The promise of immunotherapy in genitourinary malignancies. Precis Clin Med. 2018 Dec;1(3):97–101.

Published In

Precis Clin Med

DOI

EISSN

2516-1571

Publication Date

December 2018

Volume

1

Issue

3

Start / End Page

97 / 101

Location

England