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Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol.

Publication ,  Journal Article
Levy, SB; Dulichan, AM; Helman, M
Published in: Cutan Ocul Toxicol
2009

To study the potential for delayed Type IV dermal sensitivity of a new preservative system containing 1,2-hexanediol and caprylyl glycol, 200-subject repeat insult patch tests were performed with a 15% mixture of 1,2-hexanediol and caprylyl glycol (equal parts of the 2 ingredients) in carbomer gel and a cosmetic formulation at an actual use concentration. No delayed Type IV hypersensitivity reactions were observed.

Duke Scholars

Published In

Cutan Ocul Toxicol

DOI

EISSN

1556-9535

Publication Date

2009

Volume

28

Issue

1

Start / End Page

23 / 24

Location

England

Related Subject Headings

  • Young Adult
  • Toxicology
  • Preservatives, Pharmaceutical
  • Patch Tests
  • Octanols
  • Middle Aged
  • Male
  • Hypersensitivity, Delayed
  • Humans
  • Hexanes
 

Citation

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Levy, S. B., Dulichan, A. M., & Helman, M. (2009). Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol. Cutan Ocul Toxicol, 28(1), 23–24. https://doi.org/10.1080/15569520802636082
Levy, Stanley B., Anthony M. Dulichan, and Michael Helman. “Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol.Cutan Ocul Toxicol 28, no. 1 (2009): 23–24. https://doi.org/10.1080/15569520802636082.
Levy SB, Dulichan AM, Helman M. Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol. Cutan Ocul Toxicol. 2009;28(1):23–4.
Levy, Stanley B., et al. “Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol.Cutan Ocul Toxicol, vol. 28, no. 1, 2009, pp. 23–24. Pubmed, doi:10.1080/15569520802636082.
Levy SB, Dulichan AM, Helman M. Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol. Cutan Ocul Toxicol. 2009;28(1):23–24.

Published In

Cutan Ocul Toxicol

DOI

EISSN

1556-9535

Publication Date

2009

Volume

28

Issue

1

Start / End Page

23 / 24

Location

England

Related Subject Headings

  • Young Adult
  • Toxicology
  • Preservatives, Pharmaceutical
  • Patch Tests
  • Octanols
  • Middle Aged
  • Male
  • Hypersensitivity, Delayed
  • Humans
  • Hexanes