Fibroblast growth factor receptor 4: the missing link between chronic kidney disease and FGF23-induced left ventricular hypertrophy?
Publication
, Journal Article
Wyatt, CM; Drüeke, TB
Published in: Kidney Int
January 2016
Serum phosphorus and the regulatory hormone fibroblast growth factor 23 have been strongly linked to cardiovascular morbidity and mortality in patients with chronic kidney disease. A recent study identified fibroblast growth factor receptor 4 as the primary receptor mediating the effect of fibroblast growth factor 23 on left ventricular hypertrophy, providing new mechanistic insights and a potential therapeutic target to reduce cardiovascular morbidity in chronic kidney disease.
Duke Scholars
Published In
Kidney Int
DOI
EISSN
1523-1755
Publication Date
January 2016
Volume
89
Issue
1
Start / End Page
7 / 9
Location
United States
Related Subject Headings
- Urology & Nephrology
- Receptor, Fibroblast Growth Factor, Type 4
- Rats
- Phosphorus
- Mice
- Klotho Proteins
- Kidney Failure, Chronic
- Hypertrophy, Left Ventricular
- Humans
- Glucuronidase
Citation
APA
Chicago
ICMJE
MLA
NLM
Wyatt, C. M., & Drüeke, T. B. (2016). Fibroblast growth factor receptor 4: the missing link between chronic kidney disease and FGF23-induced left ventricular hypertrophy? Kidney Int, 89(1), 7–9. https://doi.org/10.1016/j.kint.2015.11.012
Wyatt, Christina M., and Tilman B. Drüeke. “Fibroblast growth factor receptor 4: the missing link between chronic kidney disease and FGF23-induced left ventricular hypertrophy?” Kidney Int 89, no. 1 (January 2016): 7–9. https://doi.org/10.1016/j.kint.2015.11.012.
Wyatt CM, Drüeke TB. Fibroblast growth factor receptor 4: the missing link between chronic kidney disease and FGF23-induced left ventricular hypertrophy? Kidney Int. 2016 Jan;89(1):7–9.
Wyatt, Christina M., and Tilman B. Drüeke. “Fibroblast growth factor receptor 4: the missing link between chronic kidney disease and FGF23-induced left ventricular hypertrophy?” Kidney Int, vol. 89, no. 1, Jan. 2016, pp. 7–9. Pubmed, doi:10.1016/j.kint.2015.11.012.
Wyatt CM, Drüeke TB. Fibroblast growth factor receptor 4: the missing link between chronic kidney disease and FGF23-induced left ventricular hypertrophy? Kidney Int. 2016 Jan;89(1):7–9.
Published In
Kidney Int
DOI
EISSN
1523-1755
Publication Date
January 2016
Volume
89
Issue
1
Start / End Page
7 / 9
Location
United States
Related Subject Headings
- Urology & Nephrology
- Receptor, Fibroblast Growth Factor, Type 4
- Rats
- Phosphorus
- Mice
- Klotho Proteins
- Kidney Failure, Chronic
- Hypertrophy, Left Ventricular
- Humans
- Glucuronidase