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Psychological intervention based on psychoneuroimmunology improves clinical evolution, quality of life, and immunity of children with leukemia: A preliminary study.

Publication ,  Journal Article
Chacin-Fernández, J; Chacin Fuenmayor, M; Piñerua-Shuhaibar, L; Suarez-Roca, H
Published in: Health psychology open
January 2019

We conducted a non-randomized, open-label clinical trial to assess whether a psychoneuroimmunology-based intervention enhanced immunity in children with acute lymphoblastic leukemia undergoing chemotherapy. In total, 16 children (44% female) received psychoneuroimmunology-based intervention, whereas 12 (50% female) received health psychoeducation (controls). The primary outcome was immunity markers, being clinical conditions the secondary outcome. Psychoneuroimmunology-based intervention increased immune markers (CD8+ T, B, and natural killer cells, serum immunoglobulin A, and immunoglobulin M) and quality of life, whereas it shortens the duration of fever and use of antipyretics, antibiotics, analgesics, and respiratory therapy. Immunity markers correlated with clinical conditions. Thus, psychoneuroimmunology-based intervention could reduce hospital cost and increase patient well-being.

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Published In

Health psychology open

DOI

EISSN

2055-1029

ISSN

2055-1029

Publication Date

January 2019

Volume

6

Issue

1

Start / End Page

2055102919838902

Related Subject Headings

  • 5205 Social and personality psychology
  • 5203 Clinical and health psychology
  • 1701 Psychology
 

Citation

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Chacin-Fernández, J., Chacin Fuenmayor, M., Piñerua-Shuhaibar, L., & Suarez-Roca, H. (2019). Psychological intervention based on psychoneuroimmunology improves clinical evolution, quality of life, and immunity of children with leukemia: A preliminary study. Health Psychology Open, 6(1), 2055102919838902. https://doi.org/10.1177/2055102919838902
Chacin-Fernández, Josymar, Margarita Chacin Fuenmayor, Lorena Piñerua-Shuhaibar, and Heberto Suarez-Roca. “Psychological intervention based on psychoneuroimmunology improves clinical evolution, quality of life, and immunity of children with leukemia: A preliminary study.Health Psychology Open 6, no. 1 (January 2019): 2055102919838902. https://doi.org/10.1177/2055102919838902.
Chacin-Fernández J, Chacin Fuenmayor M, Piñerua-Shuhaibar L, Suarez-Roca H. Psychological intervention based on psychoneuroimmunology improves clinical evolution, quality of life, and immunity of children with leukemia: A preliminary study. Health psychology open. 2019 Jan;6(1):2055102919838902.
Chacin-Fernández, Josymar, et al. “Psychological intervention based on psychoneuroimmunology improves clinical evolution, quality of life, and immunity of children with leukemia: A preliminary study.Health Psychology Open, vol. 6, no. 1, Jan. 2019, p. 2055102919838902. Epmc, doi:10.1177/2055102919838902.
Chacin-Fernández J, Chacin Fuenmayor M, Piñerua-Shuhaibar L, Suarez-Roca H. Psychological intervention based on psychoneuroimmunology improves clinical evolution, quality of life, and immunity of children with leukemia: A preliminary study. Health psychology open. 2019 Jan;6(1):2055102919838902.
Journal cover image

Published In

Health psychology open

DOI

EISSN

2055-1029

ISSN

2055-1029

Publication Date

January 2019

Volume

6

Issue

1

Start / End Page

2055102919838902

Related Subject Headings

  • 5205 Social and personality psychology
  • 5203 Clinical and health psychology
  • 1701 Psychology