Mitochondrial DNA variation in human metabolic rate and energy expenditure.
Publication
, Journal Article
Tranah, GJ; Manini, TM; Lohman, KK; Nalls, MA; Kritchevsky, S; Newman, AB; Harris, TB; Miljkovic, I; Biffi, A; Cummings, SR; Liu, Y
Published in: Mitochondrion
November 2011
The role of climate in driving selection of mtDNA as Homo sapiens migrated out of Africa into Eurasia remains controversial. We evaluated the role of mtDNA variation in resting metabolic rate (RMR) and total energy expenditure (TEE) among 294 older, community-dwelling African and European American adults from the Health, Aging and Body Composition Study. Common African haplogroups L0, L2 and L3 had significantly lower RMRs than European haplogroups H, JT and UK with haplogroup L1 RMR being intermediate to these groups. This study links mitochondrial haplogroups with ancestry-associated differences in metabolic rate and energy expenditure.
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Published In
Mitochondrion
DOI
EISSN
1872-8278
Publication Date
November 2011
Volume
11
Issue
6
Start / End Page
855 / 861
Location
Netherlands
Related Subject Headings
- White People
- United States
- Male
- Humans
- Haplotypes
- Genetic Variation
- Female
- Energy Metabolism
- DNA, Mitochondrial
- Black or African American
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Tranah, G. J., Manini, T. M., Lohman, K. K., Nalls, M. A., Kritchevsky, S., Newman, A. B., … Liu, Y. (2011). Mitochondrial DNA variation in human metabolic rate and energy expenditure. Mitochondrion, 11(6), 855–861. https://doi.org/10.1016/j.mito.2011.04.005
Tranah, Gregory J., Todd M. Manini, Kurt K. Lohman, Michael A. Nalls, Stephen Kritchevsky, Anne B. Newman, Tamara B. Harris, et al. “Mitochondrial DNA variation in human metabolic rate and energy expenditure.” Mitochondrion 11, no. 6 (November 2011): 855–61. https://doi.org/10.1016/j.mito.2011.04.005.
Tranah GJ, Manini TM, Lohman KK, Nalls MA, Kritchevsky S, Newman AB, et al. Mitochondrial DNA variation in human metabolic rate and energy expenditure. Mitochondrion. 2011 Nov;11(6):855–61.
Tranah, Gregory J., et al. “Mitochondrial DNA variation in human metabolic rate and energy expenditure.” Mitochondrion, vol. 11, no. 6, Nov. 2011, pp. 855–61. Pubmed, doi:10.1016/j.mito.2011.04.005.
Tranah GJ, Manini TM, Lohman KK, Nalls MA, Kritchevsky S, Newman AB, Harris TB, Miljkovic I, Biffi A, Cummings SR, Liu Y. Mitochondrial DNA variation in human metabolic rate and energy expenditure. Mitochondrion. 2011 Nov;11(6):855–861.
Published In
Mitochondrion
DOI
EISSN
1872-8278
Publication Date
November 2011
Volume
11
Issue
6
Start / End Page
855 / 861
Location
Netherlands
Related Subject Headings
- White People
- United States
- Male
- Humans
- Haplotypes
- Genetic Variation
- Female
- Energy Metabolism
- DNA, Mitochondrial
- Black or African American