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Pathogenesis of Posttraumatic Osteoarthritis of the Ankle.

Publication ,  Journal Article
Nwankwo, EC; Labaran, LA; Athas, V; Olson, S; Adams, SB
Published in: Orthop Clin North Am
October 2019

Ankle osteoarthritis affects a significant portion of the global adult population. Unlike other joints, arthritis of the ankle often develops as a response to traumatic injury (intra-articular fracture) of the ankle joints. The full mechanism leading to posttraumatic osteoarthritis of the ankle (PTOAA) is poorly understood. These deficits in knowledge pose challenges in the management of the disease. Adequate surgical reduction of fractured ankle joints remains the gold standard in prevention. The purpose of this review is to thoroughly delineate the known pathogenesis of PTOAA, and provide critical updates on this pathology and new avenues to provide therapeutic management of the disease.

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Published In

Orthop Clin North Am

DOI

EISSN

1558-1373

Publication Date

October 2019

Volume

50

Issue

4

Start / End Page

529 / 537

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Osteoarthritis
  • Orthopedics
  • Lipid Metabolism
  • Humans
  • Fracture Fixation, Internal
  • Disease Management
  • Biomechanical Phenomena
  • Ankle Fractures
  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
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Nwankwo, E. C., Labaran, L. A., Athas, V., Olson, S., & Adams, S. B. (2019). Pathogenesis of Posttraumatic Osteoarthritis of the Ankle. Orthop Clin North Am, 50(4), 529–537. https://doi.org/10.1016/j.ocl.2019.05.008
Nwankwo, Eugene C., Lawal A. Labaran, Vincent Athas, Steve Olson, and Samuel B. Adams. “Pathogenesis of Posttraumatic Osteoarthritis of the Ankle.Orthop Clin North Am 50, no. 4 (October 2019): 529–37. https://doi.org/10.1016/j.ocl.2019.05.008.
Nwankwo EC, Labaran LA, Athas V, Olson S, Adams SB. Pathogenesis of Posttraumatic Osteoarthritis of the Ankle. Orthop Clin North Am. 2019 Oct;50(4):529–37.
Nwankwo, Eugene C., et al. “Pathogenesis of Posttraumatic Osteoarthritis of the Ankle.Orthop Clin North Am, vol. 50, no. 4, Oct. 2019, pp. 529–37. Pubmed, doi:10.1016/j.ocl.2019.05.008.
Nwankwo EC, Labaran LA, Athas V, Olson S, Adams SB. Pathogenesis of Posttraumatic Osteoarthritis of the Ankle. Orthop Clin North Am. 2019 Oct;50(4):529–537.
Journal cover image

Published In

Orthop Clin North Am

DOI

EISSN

1558-1373

Publication Date

October 2019

Volume

50

Issue

4

Start / End Page

529 / 537

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Osteoarthritis
  • Orthopedics
  • Lipid Metabolism
  • Humans
  • Fracture Fixation, Internal
  • Disease Management
  • Biomechanical Phenomena
  • Ankle Fractures
  • 3202 Clinical sciences