Exercise-associated amenorrhea: are altered leptin levels an early warning sign?

Although the exact cause of the female athlete triad (amenorrhea, disordered eating, and osteoporosis) is unknown, recent research implicates leptin, a hormone that is secreted by adipocytes. Leptin may be an important indicator of nutritional status and may also play a role in reproductive function. Physicians who develop a plan for early recognition and treatment of exercise-induced amenorrhea now may prevent the more serious consequences of osteopenia and osteoporosis later.

Duke Scholars

Author Emily Meredith D'Agostino Orthopaedic Surgery, Occupational Therapy