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The role of chemotherapy in the treatment of central neurocytoma.

Publication ,  Journal Article
Johnson, MO; Kirkpatrick, JP; Patel, MP; Desjardins, A; Randazzo, DM; Friedman, HS; Ashley, DM; Peters, KB
Published in: CNS Oncol
November 1, 2019

Aim: Central neurocytoma (CN) is a rare WHO grade II central nervous system (CNS) tumor. This is an update on chemotherapeutic agents used in its treatment. Patients & methods: An institutional review board-approved, chart review of patients seen at our institution resulted in a single case treated with chemotherapy and is herein included. We proceeded with a comprehensive literature review. Results: We identified 18 citations, representing 39 cases of adult and pediatric CN treated with chemotherapy. With the addition of our single case, the total number of recurrent CN patients treated with temozolomide (TMZ) is nine. Conclusion: There exists marked heterogeneity in chemotherapy used to treat CN. TMZ is incorporated into treatment regimens in the setting of tumor recurrence: its role merits further study.

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Published In

CNS Oncol

DOI

EISSN

2045-0915

Publication Date

November 1, 2019

Volume

8

Issue

3

Start / End Page

CNS41

Location

England

Related Subject Headings

  • Treatment Outcome
  • Neurocytoma
  • Humans
  • Brain Neoplasms
  • Antineoplastic Agents
  • 3211 Oncology and carcinogenesis
 

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Johnson, M. O., Kirkpatrick, J. P., Patel, M. P., Desjardins, A., Randazzo, D. M., Friedman, H. S., … Peters, K. B. (2019). The role of chemotherapy in the treatment of central neurocytoma. CNS Oncol, 8(3), CNS41. https://doi.org/10.2217/cns-2019-0012
Johnson, Margaret O., John P. Kirkpatrick, Mallika P. Patel, Annick Desjardins, Dina M. Randazzo, Henry S. Friedman, David M. Ashley, and Katherine B. Peters. “The role of chemotherapy in the treatment of central neurocytoma.CNS Oncol 8, no. 3 (November 1, 2019): CNS41. https://doi.org/10.2217/cns-2019-0012.
Johnson MO, Kirkpatrick JP, Patel MP, Desjardins A, Randazzo DM, Friedman HS, et al. The role of chemotherapy in the treatment of central neurocytoma. CNS Oncol. 2019 Nov 1;8(3):CNS41.
Johnson, Margaret O., et al. “The role of chemotherapy in the treatment of central neurocytoma.CNS Oncol, vol. 8, no. 3, Nov. 2019, p. CNS41. Pubmed, doi:10.2217/cns-2019-0012.
Johnson MO, Kirkpatrick JP, Patel MP, Desjardins A, Randazzo DM, Friedman HS, Ashley DM, Peters KB. The role of chemotherapy in the treatment of central neurocytoma. CNS Oncol. 2019 Nov 1;8(3):CNS41.
Journal cover image

Published In

CNS Oncol

DOI

EISSN

2045-0915

Publication Date

November 1, 2019

Volume

8

Issue

3

Start / End Page

CNS41

Location

England

Related Subject Headings

  • Treatment Outcome
  • Neurocytoma
  • Humans
  • Brain Neoplasms
  • Antineoplastic Agents
  • 3211 Oncology and carcinogenesis