Reprogramming of cellular metabolic pathways by human oncogenic viruses.
Publication
, Journal Article
Purdy, JG; Luftig, MA
Published in: Curr Opin Virol
December 2019
Oncogenic viruses, like all viruses, relies on host metabolism to provide the metabolites and energy needed for virus replication. Many DNA tumor viruses and retroviruses will reprogram metabolism during infection. Additionally, some viral oncogenes may alter metabolism independent of virus replication. Virus infection and cancer development share many similarities regarding metabolic reprogramming as both processes demand increased metabolic activity to produce biomass: cell proliferation in the case of cancer and virion production in the case of infection. This review discusses the parallels in metabolic reprogramming between human oncogenic viruses and oncogenesis.
Duke Scholars
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Published In
Curr Opin Virol
DOI
EISSN
1879-6265
Publication Date
December 2019
Volume
39
Start / End Page
60 / 69
Location
Netherlands
Related Subject Headings
- Virus Replication
- Virion
- Retroviridae
- Papillomaviridae
- Oncogenic Viruses
- Neoplasms
- Metabolic Networks and Pathways
- Merkel cell polyomavirus
- Humans
- Herpesviridae
Citation
APA
Chicago
ICMJE
MLA
NLM
Purdy, J. G., & Luftig, M. A. (2019). Reprogramming of cellular metabolic pathways by human oncogenic viruses. Curr Opin Virol, 39, 60–69. https://doi.org/10.1016/j.coviro.2019.11.002
Purdy, John G., and Micah A. Luftig. “Reprogramming of cellular metabolic pathways by human oncogenic viruses.” Curr Opin Virol 39 (December 2019): 60–69. https://doi.org/10.1016/j.coviro.2019.11.002.
Purdy JG, Luftig MA. Reprogramming of cellular metabolic pathways by human oncogenic viruses. Curr Opin Virol. 2019 Dec;39:60–9.
Purdy, John G., and Micah A. Luftig. “Reprogramming of cellular metabolic pathways by human oncogenic viruses.” Curr Opin Virol, vol. 39, Dec. 2019, pp. 60–69. Pubmed, doi:10.1016/j.coviro.2019.11.002.
Purdy JG, Luftig MA. Reprogramming of cellular metabolic pathways by human oncogenic viruses. Curr Opin Virol. 2019 Dec;39:60–69.
Published In
Curr Opin Virol
DOI
EISSN
1879-6265
Publication Date
December 2019
Volume
39
Start / End Page
60 / 69
Location
Netherlands
Related Subject Headings
- Virus Replication
- Virion
- Retroviridae
- Papillomaviridae
- Oncogenic Viruses
- Neoplasms
- Metabolic Networks and Pathways
- Merkel cell polyomavirus
- Humans
- Herpesviridae