Identification and characterization of a human homolog of the Schizosaccharomyces pombe ras-like gene YPT-3.
Publication
, Journal Article
Drivas, GT; Shih, A; Coutavas, EE; D'Eustachio, P; Rush, MG
Published in: Oncogene
January 1991
The Polymerase Chain Reaction was used to amplify ras and ras-like sequences from two human cDNA libraries. Members corresponding to each of the three major ras-subfamilies (ras, rho, and rab/YPT) were identified. The one homologous to rab/YPT, referred to here as YL8, appears to be the human homolog of the recently reported Schizosaccharomyces pombe YPT3 gene. The YL8 gene could encode a guanine nucleotide binding protein of 216 amino acids with about 70% amino acid sequence identity to S. pombe YPT3, and is transcriptionally active in a variety of human cell lines.
Duke Scholars
Published In
Oncogene
ISSN
0950-9232
Publication Date
January 1991
Volume
6
Issue
1
Start / End Page
3 / 9
Location
England
Related Subject Headings
- Sequence Homology, Nucleic Acid
- Schizosaccharomyces
- Saccharomyces cerevisiae
- RNA
- Polymerase Chain Reaction
- Oncology & Carcinogenesis
- Molecular Sequence Data
- Humans
- Genes, ras
- DNA
Citation
APA
Chicago
ICMJE
MLA
NLM
Drivas, G. T., Shih, A., Coutavas, E. E., D’Eustachio, P., & Rush, M. G. (1991). Identification and characterization of a human homolog of the Schizosaccharomyces pombe ras-like gene YPT-3. Oncogene, 6(1), 3–9.
Drivas, G. T., A. Shih, E. E. Coutavas, P. D’Eustachio, and M. G. Rush. “Identification and characterization of a human homolog of the Schizosaccharomyces pombe ras-like gene YPT-3.” Oncogene 6, no. 1 (January 1991): 3–9.
Drivas GT, Shih A, Coutavas EE, D’Eustachio P, Rush MG. Identification and characterization of a human homolog of the Schizosaccharomyces pombe ras-like gene YPT-3. Oncogene. 1991 Jan;6(1):3–9.
Drivas, G. T., et al. “Identification and characterization of a human homolog of the Schizosaccharomyces pombe ras-like gene YPT-3.” Oncogene, vol. 6, no. 1, Jan. 1991, pp. 3–9.
Drivas GT, Shih A, Coutavas EE, D’Eustachio P, Rush MG. Identification and characterization of a human homolog of the Schizosaccharomyces pombe ras-like gene YPT-3. Oncogene. 1991 Jan;6(1):3–9.
Published In
Oncogene
ISSN
0950-9232
Publication Date
January 1991
Volume
6
Issue
1
Start / End Page
3 / 9
Location
England
Related Subject Headings
- Sequence Homology, Nucleic Acid
- Schizosaccharomyces
- Saccharomyces cerevisiae
- RNA
- Polymerase Chain Reaction
- Oncology & Carcinogenesis
- Molecular Sequence Data
- Humans
- Genes, ras
- DNA