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Mucosal Vaccines Innovation for Preventing Infectious Diseases

Innate Immunity-Based Mucosal Modulators and Adjuvants

Publication ,  Chapter
Johnson-Weaver, B; Abraham, S; Staats, H
September 15, 2019

The development of mucosally administered vaccines remains a goal of many researchers who desire to develop a needle-free method of immunization that can induce antigen-specific immune responses in both systemic and mucosal tissues. The coadministration of adjuvants is often required to maximize the induction of protective immunity following mucosal vaccination, especially when subunit immunogens are used. A major class of mucosal vaccine adjuvants and modulators includes substances that can activate the innate immune system. Innate immune system activators that exhibit mucosal vaccine adjuvant and modulator activity will be discussed, including proinflammatory cytokines, nanoemulsions, mast cell activators, and toll-like receptor ligands.

Duke Scholars

ISBN

9780128119242

Publication Date

September 15, 2019

Publisher

Academic Press
 

Citation

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Johnson-Weaver, B., Abraham, S., & Staats, H. (2019). Innate Immunity-Based Mucosal Modulators and Adjuvants. In H. Kiyono & D. Pascual (Eds.), Mucosal Vaccines Innovation for Preventing Infectious Diseases. Academic Press.
Johnson-Weaver, Brandi, Soman Abraham, and Herman Staats. “Innate Immunity-Based Mucosal Modulators and Adjuvants.” In Mucosal Vaccines Innovation for Preventing Infectious Diseases, edited by Hiroshi Kiyono and David Pascual. Academic Press, 2019.
Johnson-Weaver B, Abraham S, Staats H. Innate Immunity-Based Mucosal Modulators and Adjuvants. In: Kiyono H, Pascual D, editors. Mucosal Vaccines Innovation for Preventing Infectious Diseases. Academic Press; 2019.
Johnson-Weaver, Brandi, et al. “Innate Immunity-Based Mucosal Modulators and Adjuvants.” Mucosal Vaccines Innovation for Preventing Infectious Diseases, edited by Hiroshi Kiyono and David Pascual, Academic Press, 2019.
Johnson-Weaver B, Abraham S, Staats H. Innate Immunity-Based Mucosal Modulators and Adjuvants. In: Kiyono H, Pascual D, editors. Mucosal Vaccines Innovation for Preventing Infectious Diseases. Academic Press; 2019.
Journal cover image

ISBN

9780128119242

Publication Date

September 15, 2019

Publisher

Academic Press