Child Neurology: A young child with an undiagnosed case of dystonia responsive to l-dopa.
Publication
, Journal Article
Trau, SP; Gallentine, WB; Mikati, MA
Published in: Neurology
February 18, 2020
Childhood-onset dystonias are a heterogeneously diverse group. There exists a specific set of dystonias that respond profoundly well to low doses of l-dopa (dopa-responsive dystonia [DRD]). Classical DRD is caused by deficiency of GTP cyclohydrolase 1 or tyrosine hydroxylase, but other conditions can cause dystonias that are partially responsive to dopamine. The idea of a diagnostic therapeutic trial with l-dopa for children who present with dystonia has been around for decades and is frequently advocated for; however, l-dopa trials are not without risk.
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Published In
Neurology
DOI
EISSN
1526-632X
Publication Date
February 18, 2020
Volume
94
Issue
7
Start / End Page
326 / 328
Location
United States
Related Subject Headings
- Neurology & Neurosurgery
- Male
- Levodopa
- Humans
- Dystonic Disorders
- Drug Combinations
- Diagnosis, Differential
- Child, Preschool
- Carbidopa
- Anti-Dyskinesia Agents
Citation
APA
Chicago
ICMJE
MLA
NLM
Trau, S. P., Gallentine, W. B., & Mikati, M. A. (2020). Child Neurology: A young child with an undiagnosed case of dystonia responsive to l-dopa. Neurology, 94(7), 326–328. https://doi.org/10.1212/WNL.0000000000008963
Trau, Steven P., William B. Gallentine, and Mohamad A. Mikati. “Child Neurology: A young child with an undiagnosed case of dystonia responsive to l-dopa.” Neurology 94, no. 7 (February 18, 2020): 326–28. https://doi.org/10.1212/WNL.0000000000008963.
Trau SP, Gallentine WB, Mikati MA. Child Neurology: A young child with an undiagnosed case of dystonia responsive to l-dopa. Neurology. 2020 Feb 18;94(7):326–8.
Trau, Steven P., et al. “Child Neurology: A young child with an undiagnosed case of dystonia responsive to l-dopa.” Neurology, vol. 94, no. 7, Feb. 2020, pp. 326–28. Pubmed, doi:10.1212/WNL.0000000000008963.
Trau SP, Gallentine WB, Mikati MA. Child Neurology: A young child with an undiagnosed case of dystonia responsive to l-dopa. Neurology. 2020 Feb 18;94(7):326–328.
Published In
Neurology
DOI
EISSN
1526-632X
Publication Date
February 18, 2020
Volume
94
Issue
7
Start / End Page
326 / 328
Location
United States
Related Subject Headings
- Neurology & Neurosurgery
- Male
- Levodopa
- Humans
- Dystonic Disorders
- Drug Combinations
- Diagnosis, Differential
- Child, Preschool
- Carbidopa
- Anti-Dyskinesia Agents