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Comparison of Modified Posterior Sub-Tenon's vs. Trans-Septal Triamcinolone Injection for Non-infectious Uveitis.

Publication ,  Journal Article
McKay, KM; Borkar, DS; Sevgi, DD; Susarla, G; Papaliodis, GN; Sobrin, L
Published in: Ocul Immunol Inflamm
July 4, 2021

Purpose: To compare the safety and efficacy of trans-septal vs. modified posterior sub-Tenon's (PST) corticosteroid injections for noninfectious uveitis.Methods: Retrospective comparison of periocular triamcinolone injection by modified PST (n = 36) vs. traditional trans-septal (n = 79) techniques. Safety and efficacy outcomes were analyzed with regression models.Results: There was no significant difference in visual acuity improvement between the groups at 6 months. There were higher rates of vitritis resolution in the modified PST group but this was not statistically significant (85.7% vs 62.9%, p = .07). Intraocular pressure (IOP) elevation rate trended higher with the modified PST injection (21.9% vs 9.0%, p = .06), with no instances of glaucoma surgery in either group. Two modified PST injection patients with refractory IOP rises had IOP normalization after corticosteroid depot removal. One year cataract surgery rates were similar.Conclusion: Modified PST injection offers clinical efficacy but with possibly higher IOP response rate which could be managed with corticosteroid removal.

Duke Scholars

Published In

Ocul Immunol Inflamm

DOI

EISSN

1744-5078

Publication Date

July 4, 2021

Volume

29

Issue

5

Start / End Page

857 / 864

Location

England

Related Subject Headings

  • Visual Acuity
  • Uveitis
  • Triamcinolone Acetonide
  • Treatment Outcome
  • Tenon Capsule
  • Retrospective Studies
  • Ophthalmology & Optometry
  • Middle Aged
  • Male
  • Macular Edema
 

Citation

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McKay, K. M., Borkar, D. S., Sevgi, D. D., Susarla, G., Papaliodis, G. N., & Sobrin, L. (2021). Comparison of Modified Posterior Sub-Tenon's vs. Trans-Septal Triamcinolone Injection for Non-infectious Uveitis. Ocul Immunol Inflamm, 29(5), 857–864. https://doi.org/10.1080/09273948.2019.1698748
McKay, K Matthew, Durga S. Borkar, Duriye Damla Sevgi, Gayatri Susarla, George N. Papaliodis, and Lucia Sobrin. “Comparison of Modified Posterior Sub-Tenon's vs. Trans-Septal Triamcinolone Injection for Non-infectious Uveitis.Ocul Immunol Inflamm 29, no. 5 (July 4, 2021): 857–64. https://doi.org/10.1080/09273948.2019.1698748.
McKay KM, Borkar DS, Sevgi DD, Susarla G, Papaliodis GN, Sobrin L. Comparison of Modified Posterior Sub-Tenon's vs. Trans-Septal Triamcinolone Injection for Non-infectious Uveitis. Ocul Immunol Inflamm. 2021 Jul 4;29(5):857–64.
McKay, K. Matthew, et al. “Comparison of Modified Posterior Sub-Tenon's vs. Trans-Septal Triamcinolone Injection for Non-infectious Uveitis.Ocul Immunol Inflamm, vol. 29, no. 5, July 2021, pp. 857–64. Pubmed, doi:10.1080/09273948.2019.1698748.
McKay KM, Borkar DS, Sevgi DD, Susarla G, Papaliodis GN, Sobrin L. Comparison of Modified Posterior Sub-Tenon's vs. Trans-Septal Triamcinolone Injection for Non-infectious Uveitis. Ocul Immunol Inflamm. 2021 Jul 4;29(5):857–864.

Published In

Ocul Immunol Inflamm

DOI

EISSN

1744-5078

Publication Date

July 4, 2021

Volume

29

Issue

5

Start / End Page

857 / 864

Location

England

Related Subject Headings

  • Visual Acuity
  • Uveitis
  • Triamcinolone Acetonide
  • Treatment Outcome
  • Tenon Capsule
  • Retrospective Studies
  • Ophthalmology & Optometry
  • Middle Aged
  • Male
  • Macular Edema