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Genomic and Precision Medicine: Infectious and Inflammatory Disease

The microbiota and infectious diseases

Publication ,  Chapter
Surana, NK
January 1, 2019

Studies over the last decade have transformed our previously simplistic view of microbes having only a pathogenic role in disease to a more robust understanding that they are critical for maintaining human health. Indeed, our microbiota-the collection of commensal organisms that live in and on each of us-contributes to nearly every facet of host physiology, from metabolic functions to maturation of the immune system and everything in between. Although the specific details of these host-microbe interactions are still being elucidated for most diseases, the marriage of clinical samples with animal models of disease have provided key insights. This chapter provides some general background on the microbiota, highlights a few examples of how the microbiota influences infectious diseases, and provides some context for how these findings may be clinically translatable.

Duke Scholars

DOI

ISBN

9780128014967

Publication Date

January 1, 2019

Start / End Page

445 / 457
 

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Surana, N. K. (2019). The microbiota and infectious diseases. In Genomic and Precision Medicine: Infectious and Inflammatory Disease (pp. 445–457). https://doi.org/10.1016/B978-0-12-801496-7.00023-X
Surana, N. K. “The microbiota and infectious diseases.” In Genomic and Precision Medicine: Infectious and Inflammatory Disease, 445–57, 2019. https://doi.org/10.1016/B978-0-12-801496-7.00023-X.
Surana NK. The microbiota and infectious diseases. In: Genomic and Precision Medicine: Infectious and Inflammatory Disease. 2019. p. 445–57.
Surana, N. K. “The microbiota and infectious diseases.” Genomic and Precision Medicine: Infectious and Inflammatory Disease, 2019, pp. 445–57. Scopus, doi:10.1016/B978-0-12-801496-7.00023-X.
Surana NK. The microbiota and infectious diseases. Genomic and Precision Medicine: Infectious and Inflammatory Disease. 2019. p. 445–457.
Journal cover image

DOI

ISBN

9780128014967

Publication Date

January 1, 2019

Start / End Page

445 / 457