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Heart failure with mid-range ejection fraction: pro and cons of the new classification of Heart Failure by European Society of Cardiology guidelines.

Publication ,  Journal Article
Branca, L; Sbolli, M; Metra, M; Fudim, M
Published in: ESC Heart Fail
April 2020

Currently, the assessment of left ventricular ejection fraction (LVEF) is the cornerstone of the classification of patients with heart failure (HF). The mid-range LVEF (HFmrEF) category was identified in an attempt to uncover specific characteristics of these patients. So far, the analysis of trials, registries, and observational studies have demonstrated that patients with mid-range LVEF belong to a patient cohort with generally intermediate clinical profile as compared with other groups but with a remarkable variety of intrinsic phenotypes. This is due to the limitations of LVEF as the sole criterion to categorize patients with HF and characterize their prognosis, above all when it is >40%. To better define the HFmrEF phenotype, it is reasonable to consider other parameters, such as LVEF changes over time, HF aetiology, co-morbidities, and other imaging parameters. A multiparametric evaluation may contextualize a patient with HFmrEF in a more defined phenotype with a specific prognosis.

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Published In

ESC Heart Fail

DOI

EISSN

2055-5822

Publication Date

April 2020

Volume

7

Issue

2

Start / End Page

381 / 399

Location

England

Related Subject Headings

  • Ventricular Function, Left
  • Stroke Volume
  • Prognosis
  • Humans
  • Heart Failure
  • Cardiology
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology
 

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Branca, L., Sbolli, M., Metra, M., & Fudim, M. (2020). Heart failure with mid-range ejection fraction: pro and cons of the new classification of Heart Failure by European Society of Cardiology guidelines. ESC Heart Fail, 7(2), 381–399. https://doi.org/10.1002/ehf2.12586
Branca, Luca, Marco Sbolli, Marco Metra, and Marat Fudim. “Heart failure with mid-range ejection fraction: pro and cons of the new classification of Heart Failure by European Society of Cardiology guidelines.ESC Heart Fail 7, no. 2 (April 2020): 381–99. https://doi.org/10.1002/ehf2.12586.
Branca, Luca, et al. “Heart failure with mid-range ejection fraction: pro and cons of the new classification of Heart Failure by European Society of Cardiology guidelines.ESC Heart Fail, vol. 7, no. 2, Apr. 2020, pp. 381–99. Pubmed, doi:10.1002/ehf2.12586.
Journal cover image

Published In

ESC Heart Fail

DOI

EISSN

2055-5822

Publication Date

April 2020

Volume

7

Issue

2

Start / End Page

381 / 399

Location

England

Related Subject Headings

  • Ventricular Function, Left
  • Stroke Volume
  • Prognosis
  • Humans
  • Heart Failure
  • Cardiology
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology