Skip to main content

Colonial differentiation in Streptomyces coelicolor depends on translation of a specific codon within the adpA gene.

Publication ,  Journal Article
Nguyen, KT; Tenor, J; Stettler, H; Nguyen, LT; Nguyen, LD; Thompson, CJ
Published in: J Bacteriol
December 2003

We identified adpA as an araC-like regulatory gene needed for colonial morphogenesis in Streptomyces coelicolor and showed that its activity depended on a unique TTA triplet corresponding to the leucyl-tRNA gene (bldA). These findings partially explained the dependence of aerial mycelium formation on a rare tRNA that is postulated to have developmental control functions.

Duke Scholars

Published In

J Bacteriol

DOI

ISSN

0021-9193

Publication Date

December 2003

Volume

185

Issue

24

Start / End Page

7291 / 7296

Location

United States

Related Subject Headings

  • Transcription, Genetic
  • Transcription Factors
  • Trans-Activators
  • Streptomyces
  • RNA, Transfer, Leu
  • RNA, Bacterial
  • Protein Biosynthesis
  • Promoter Regions, Genetic
  • Phenotype
  • Mycelium
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Nguyen, K. T., Tenor, J., Stettler, H., Nguyen, L. T., Nguyen, L. D., & Thompson, C. J. (2003). Colonial differentiation in Streptomyces coelicolor depends on translation of a specific codon within the adpA gene. J Bacteriol, 185(24), 7291–7296. https://doi.org/10.1128/JB.185.24.7291-7296.2003
Nguyen, Kien T., Jennifer Tenor, Hansruedi Stettler, Lieu T. Nguyen, Liem D. Nguyen, and Charles J. Thompson. “Colonial differentiation in Streptomyces coelicolor depends on translation of a specific codon within the adpA gene.J Bacteriol 185, no. 24 (December 2003): 7291–96. https://doi.org/10.1128/JB.185.24.7291-7296.2003.
Nguyen KT, Tenor J, Stettler H, Nguyen LT, Nguyen LD, Thompson CJ. Colonial differentiation in Streptomyces coelicolor depends on translation of a specific codon within the adpA gene. J Bacteriol. 2003 Dec;185(24):7291–6.
Nguyen, Kien T., et al. “Colonial differentiation in Streptomyces coelicolor depends on translation of a specific codon within the adpA gene.J Bacteriol, vol. 185, no. 24, Dec. 2003, pp. 7291–96. Pubmed, doi:10.1128/JB.185.24.7291-7296.2003.
Nguyen KT, Tenor J, Stettler H, Nguyen LT, Nguyen LD, Thompson CJ. Colonial differentiation in Streptomyces coelicolor depends on translation of a specific codon within the adpA gene. J Bacteriol. 2003 Dec;185(24):7291–7296.

Published In

J Bacteriol

DOI

ISSN

0021-9193

Publication Date

December 2003

Volume

185

Issue

24

Start / End Page

7291 / 7296

Location

United States

Related Subject Headings

  • Transcription, Genetic
  • Transcription Factors
  • Trans-Activators
  • Streptomyces
  • RNA, Transfer, Leu
  • RNA, Bacterial
  • Protein Biosynthesis
  • Promoter Regions, Genetic
  • Phenotype
  • Mycelium