Model systems for regeneration: Drosophila.
Publication
, Journal Article
Fox, DT; Cohen, E; Smith-Bolton, R
Published in: Development (Cambridge, England)
April 2020
Drosophila melanogaster has historically been a workhorse model organism for studying developmental biology. In addition, Drosophila is an excellent model for studying how damaged tissues and organs can regenerate. Recently, new precision approaches that enable both highly targeted injury and genetic manipulation have accelerated progress in this field. Here, we highlight these techniques and review examples of recently discovered mechanisms that regulate regeneration in Drosophila larval and adult tissues. We also discuss how, by applying these powerful approaches, studies of Drosophila can continue to guide the future of regeneration research.
Duke Scholars
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Published In
Development (Cambridge, England)
DOI
EISSN
1477-9129
ISSN
0950-1991
Publication Date
April 2020
Volume
147
Issue
7
Start / End Page
dev173781
Related Subject Headings
- Wound Healing
- Signal Transduction
- Regeneration
- Models, Biological
- Humans
- Drosophila
- Animals, Genetically Modified
- Animals
- 42 Health sciences
- 32 Biomedical and clinical sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Fox, D. T., Cohen, E., & Smith-Bolton, R. (2020). Model systems for regeneration: Drosophila. Development (Cambridge, England), 147(7), dev173781. https://doi.org/10.1242/dev.173781
Fox, Donald T., Erez Cohen, and Rachel Smith-Bolton. “Model systems for regeneration: Drosophila.” Development (Cambridge, England) 147, no. 7 (April 2020): dev173781. https://doi.org/10.1242/dev.173781.
Fox DT, Cohen E, Smith-Bolton R. Model systems for regeneration: Drosophila. Development (Cambridge, England). 2020 Apr;147(7):dev173781.
Fox, Donald T., et al. “Model systems for regeneration: Drosophila.” Development (Cambridge, England), vol. 147, no. 7, Apr. 2020, p. dev173781. Epmc, doi:10.1242/dev.173781.
Fox DT, Cohen E, Smith-Bolton R. Model systems for regeneration: Drosophila. Development (Cambridge, England). 2020 Apr;147(7):dev173781.
Published In
Development (Cambridge, England)
DOI
EISSN
1477-9129
ISSN
0950-1991
Publication Date
April 2020
Volume
147
Issue
7
Start / End Page
dev173781
Related Subject Headings
- Wound Healing
- Signal Transduction
- Regeneration
- Models, Biological
- Humans
- Drosophila
- Animals, Genetically Modified
- Animals
- 42 Health sciences
- 32 Biomedical and clinical sciences