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The enduring importance of family health history in the era of genomic medicine and risk assessment.

Publication ,  Journal Article
Haga, SB; Orlando, LA
Published in: Per Med
May 1, 2020

Improving disease risk prediction and tailoring preventive interventions to patient risk factors is one of the primary goals of precision medicine. Family health history is the traditional approach to quickly gather genetic and environmental data relevant to the patient. While the utility of family health history is well-documented, its utilization is variable, in part due to lack of patient and provider knowledge and incomplete or inaccurate data. With the advances and reduced costs of sequencing technologies, comprehensive sequencing tests can be performed as a risk assessment tool. We provide an overview of each of these risk assessment approaches, the benefits and limitations and implementation challenges.

Duke Scholars

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Published In

Per Med

DOI

EISSN

1744-828X

Publication Date

May 1, 2020

Volume

17

Issue

3

Start / End Page

229 / 239

Location

England

Related Subject Headings

  • Risk Factors
  • Risk Assessment
  • Precision Medicine
  • Pharmacology & Pharmacy
  • Medical History Taking
  • Humans
  • Genomics
  • Genetic Testing
  • 3214 Pharmacology and pharmaceutical sciences
  • 3202 Clinical sciences
 

Citation

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Haga, S. B., & Orlando, L. A. (2020). The enduring importance of family health history in the era of genomic medicine and risk assessment. Per Med, 17(3), 229–239. https://doi.org/10.2217/pme-2019-0091
Haga, Susanne B., and Lori A. Orlando. “The enduring importance of family health history in the era of genomic medicine and risk assessment.Per Med 17, no. 3 (May 1, 2020): 229–39. https://doi.org/10.2217/pme-2019-0091.
Haga, Susanne B., and Lori A. Orlando. “The enduring importance of family health history in the era of genomic medicine and risk assessment.Per Med, vol. 17, no. 3, May 2020, pp. 229–39. Pubmed, doi:10.2217/pme-2019-0091.
Journal cover image

Published In

Per Med

DOI

EISSN

1744-828X

Publication Date

May 1, 2020

Volume

17

Issue

3

Start / End Page

229 / 239

Location

England

Related Subject Headings

  • Risk Factors
  • Risk Assessment
  • Precision Medicine
  • Pharmacology & Pharmacy
  • Medical History Taking
  • Humans
  • Genomics
  • Genetic Testing
  • 3214 Pharmacology and pharmaceutical sciences
  • 3202 Clinical sciences