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Assessment of Patient Outcomes and Proximal Junctional Failure Rate of Patients with Adult Spinal Deformity Undergoing Caudal Extension of Previous Spinal Fusion.

Publication ,  Journal Article
Daniels, AH; Reid, DBC; Durand, WM; Line, B; Passias, P; Kim, HJ; Protopsaltis, T; LaFage, V; Smith, JS; Shaffrey, C; Gupta, M; Klineberg, E ...
Published in: World Neurosurg
July 2020

OBJECTIVE: This case series examined patients undergoing caudal extension of prior fusion without alteration of the prior upper instrumented vertebra (UIV) to assess patient outcomes and rates of proximal junctional kyphosis (PJK)/proximal junctional failure (PJF). METHODS: Patients eligible for 2-year minimum follow-up undergoing caudal extension of prior fusion with unchanged UIVs were identified. These patients were evaluated for PJK/PJF, and patient reported outcomes were recorded. RESULTS: In total, 40 patients were included. Mean follow-up duration was 2.2 ± 0.3 years. Patients in this cohort had poor preoperative sagittal alignment (pelvic incidence minus lumbar lordosis [PI-LL] 26.7°, T1 pelvic angle [TPA] 29.0°, sagittal vertical axis [SVA] 93.4 mm) and achieved substantial sagittal correction (ΔSVA -62.2 mm, ΔPI-LL -19.8°, ΔTPA -11.1°) after caudal extension surgery. At final follow-up, there was a 0% rate of PJF among patients undergoing caudal extension of previous fusion without creation of a new UIV, but 27.5% of patients experienced PJK. Patients experienced significant improvement in both the Oswestry Disability Index and Scoliosis Research Society-22r total score at 2 years postoperatively (P < 0.05). In total, 7.5% (n = 3) of patients underwent further revision, at an average of 1.1 ± 0.54 years after the surgery with unaltered UIV. All 3 of these patients underwent revision for rod fracture with no revisions for PJK/PJF. CONCLUSIONS: Patients undergoing caudal extension of previous fusions for sagittal alignment correction have high rates of clinical success, low revision surgery rates, and very low rates of PJF. Minimizing repetitive tissue trauma at the UIV may result in decreased PJF risk because the PJF rate in this cohort of patients with unaltered UIV is below historical PJF rates of patients undergoing sagittal balance correction.

Duke Scholars

Published In

World Neurosurg

DOI

EISSN

1878-8769

Publication Date

July 2020

Volume

139

Start / End Page

e449 / e454

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Treatment Failure
  • Spine
  • Spinal Fusion
  • Scoliosis
  • Retrospective Studies
  • Reoperation
  • Postoperative Complications
  • Middle Aged
  • Male
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Daniels, A. H., Reid, D. B. C., Durand, W. M., Line, B., Passias, P., Kim, H. J., … International Spine Study Group, . (2020). Assessment of Patient Outcomes and Proximal Junctional Failure Rate of Patients with Adult Spinal Deformity Undergoing Caudal Extension of Previous Spinal Fusion. World Neurosurg, 139, e449–e454. https://doi.org/10.1016/j.wneu.2020.04.024
Daniels, Alan H., Daniel B. C. Reid, Wesley M. Durand, Breton Line, Peter Passias, Han Jo Kim, Themistocles Protopsaltis, et al. “Assessment of Patient Outcomes and Proximal Junctional Failure Rate of Patients with Adult Spinal Deformity Undergoing Caudal Extension of Previous Spinal Fusion.World Neurosurg 139 (July 2020): e449–54. https://doi.org/10.1016/j.wneu.2020.04.024.
Daniels AH, Reid DBC, Durand WM, Line B, Passias P, Kim HJ, et al. Assessment of Patient Outcomes and Proximal Junctional Failure Rate of Patients with Adult Spinal Deformity Undergoing Caudal Extension of Previous Spinal Fusion. World Neurosurg. 2020 Jul;139:e449–54.
Daniels, Alan H., et al. “Assessment of Patient Outcomes and Proximal Junctional Failure Rate of Patients with Adult Spinal Deformity Undergoing Caudal Extension of Previous Spinal Fusion.World Neurosurg, vol. 139, July 2020, pp. e449–54. Pubmed, doi:10.1016/j.wneu.2020.04.024.
Daniels AH, Reid DBC, Durand WM, Line B, Passias P, Kim HJ, Protopsaltis T, LaFage V, Smith JS, Shaffrey C, Gupta M, Klineberg E, Schwab F, Burton D, Bess S, Ames C, Hart RA, International Spine Study Group. Assessment of Patient Outcomes and Proximal Junctional Failure Rate of Patients with Adult Spinal Deformity Undergoing Caudal Extension of Previous Spinal Fusion. World Neurosurg. 2020 Jul;139:e449–e454.
Journal cover image

Published In

World Neurosurg

DOI

EISSN

1878-8769

Publication Date

July 2020

Volume

139

Start / End Page

e449 / e454

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Treatment Failure
  • Spine
  • Spinal Fusion
  • Scoliosis
  • Retrospective Studies
  • Reoperation
  • Postoperative Complications
  • Middle Aged
  • Male