The use of ibuprofen to treat fever in COVID-19: A possible indirect association with worse outcome?
Publication
, Journal Article
Jamerson, BD; Haryadi, TH
Published in: Medical hypotheses
November 2020
Fever has been reported as a common symptom occurring in COVID-19 illness. Over the counter antipyretics such as ibuprofen and acetaminophen are often taken by individuals to reduce the discomfort of fever. Recently, the safety of ibuprofen in COVID-19 patients has been questioned due to anecdotal reports of worsening symptoms in previously healthy young adults. Studies show that ibuprofen demonstrates superior efficacy in fever reduction compared to acetaminophen. As fever may have benefit in shortening the duration of viral illness, it is plausible to hypothesize that the antipyretic efficacy of ibuprofen may be hindering the benefits of a fever response when taken during the early stages of COVID-19 illness.
Duke Scholars
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Published In
Medical hypotheses
DOI
EISSN
1532-2777
ISSN
0306-9877
Publication Date
November 2020
Volume
144
Start / End Page
109880
Related Subject Headings
- Treatment Outcome
- Patient Safety
- Neurology & Neurosurgery
- Models, Theoretical
- Ibuprofen
- Humans
- Fever
- COVID-19 Drug Treatment
- Antipyretics
- Acetaminophen
Citation
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Chicago
ICMJE
MLA
NLM
Jamerson, B. D., & Haryadi, T. H. (2020). The use of ibuprofen to treat fever in COVID-19: A possible indirect association with worse outcome? Medical Hypotheses, 144, 109880. https://doi.org/10.1016/j.mehy.2020.109880
Jamerson, Brenda D., and T Ho Haryadi. “The use of ibuprofen to treat fever in COVID-19: A possible indirect association with worse outcome?” Medical Hypotheses 144 (November 2020): 109880. https://doi.org/10.1016/j.mehy.2020.109880.
Jamerson BD, Haryadi TH. The use of ibuprofen to treat fever in COVID-19: A possible indirect association with worse outcome? Medical hypotheses. 2020 Nov;144:109880.
Jamerson, Brenda D., and T. Ho Haryadi. “The use of ibuprofen to treat fever in COVID-19: A possible indirect association with worse outcome?” Medical Hypotheses, vol. 144, Nov. 2020, p. 109880. Epmc, doi:10.1016/j.mehy.2020.109880.
Jamerson BD, Haryadi TH. The use of ibuprofen to treat fever in COVID-19: A possible indirect association with worse outcome? Medical hypotheses. 2020 Nov;144:109880.
Published In
Medical hypotheses
DOI
EISSN
1532-2777
ISSN
0306-9877
Publication Date
November 2020
Volume
144
Start / End Page
109880
Related Subject Headings
- Treatment Outcome
- Patient Safety
- Neurology & Neurosurgery
- Models, Theoretical
- Ibuprofen
- Humans
- Fever
- COVID-19 Drug Treatment
- Antipyretics
- Acetaminophen