Injectable Therapies for Regional Melanoma.
Publication
, Journal Article
Farrow, NE; Leddy, M; Landa, K; Beasley, GM
Published in: Surg Oncol Clin N Am
July 2020
Patients with unresectable cutaneous, subcutaneous, or nodal melanoma metastases are often candidates for injectable therapies, which are attractive for ease of intralesional delivery to superficial metastases and limited systemic toxicity profiles. Injectable or intralesional therapies can be part of multifaceted treatment strategies to kill tumor directly or to alter the tumor so as to make it more sensitive to systemic therapy. Talimogene laherparepvec is the only Food and Drug Administration-approved injectable therapy currently in wide clinical use in the United States, although ongoing trials are evaluating novel intralesional agents as well as combinations with systemic therapies, particularly checkpoint inhibitors.
Duke Scholars
Altmetric Attention Stats
Dimensions Citation Stats
Published In
Surg Oncol Clin N Am
DOI
EISSN
1558-5042
Publication Date
July 2020
Volume
29
Issue
3
Start / End Page
433 / 444
Location
United States
Related Subject Headings
- Oncolytic Virotherapy
- Oncology & Carcinogenesis
- Melanoma
- Immunotherapy
- Humans
- Herpesvirus 1, Human
- Biological Products
- Antineoplastic Agents, Immunological
- 3211 Oncology and carcinogenesis
- 1112 Oncology and Carcinogenesis
Citation
APA
Chicago
ICMJE
MLA
NLM
Farrow, N. E., Leddy, M., Landa, K., & Beasley, G. M. (2020). Injectable Therapies for Regional Melanoma. Surg Oncol Clin N Am, 29(3), 433–444. https://doi.org/10.1016/j.soc.2020.02.008
Farrow, Norma E., Margaret Leddy, Karenia Landa, and Georgia M. Beasley. “Injectable Therapies for Regional Melanoma.” Surg Oncol Clin N Am 29, no. 3 (July 2020): 433–44. https://doi.org/10.1016/j.soc.2020.02.008.
Farrow NE, Leddy M, Landa K, Beasley GM. Injectable Therapies for Regional Melanoma. Surg Oncol Clin N Am. 2020 Jul;29(3):433–44.
Farrow, Norma E., et al. “Injectable Therapies for Regional Melanoma.” Surg Oncol Clin N Am, vol. 29, no. 3, July 2020, pp. 433–44. Pubmed, doi:10.1016/j.soc.2020.02.008.
Farrow NE, Leddy M, Landa K, Beasley GM. Injectable Therapies for Regional Melanoma. Surg Oncol Clin N Am. 2020 Jul;29(3):433–444.
Published In
Surg Oncol Clin N Am
DOI
EISSN
1558-5042
Publication Date
July 2020
Volume
29
Issue
3
Start / End Page
433 / 444
Location
United States
Related Subject Headings
- Oncolytic Virotherapy
- Oncology & Carcinogenesis
- Melanoma
- Immunotherapy
- Humans
- Herpesvirus 1, Human
- Biological Products
- Antineoplastic Agents, Immunological
- 3211 Oncology and carcinogenesis
- 1112 Oncology and Carcinogenesis