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"Quadripolar" Transcranial Electrical Stimulation for Motor Evoked Potentials.

Publication ,  Journal Article
Schwartz, SL; Kale, EB; Madden, D; Husain, AM
Published in: J Clin Neurophysiol
January 1, 2022

PURPOSE: To determine if transcranial electrical stimulation (TES)-induced motor evoked potentials (MEPs) are of higher amplitude when using two electrodes as anodes and two as cathodes, known as "quadripolar stimulation." METHODS: Patients who underwent TES MEP monitoring in which control, bipolar stimulation and four variations of quadripolar stimulation were used were evaluated. The bipolar stimulation montage was C3-C4 (C3 was used as anode for stimulation first, then the polarity was switched to stimulate the contralateral side). Four quadripolar montages were used: C3/C1-C4/C2 (step 1), M3/M1-M4/M2 (step 2), C3/M1-C4/M2 (step 3), and M3/C1-M4/C2 (step 4). The area under the curve for the right foot TES MEP was compared for the various montages using descriptive statistics and Fisher exact test for proportions. RESULTS: Sixteen patients were retrospectively evaluated. The mean age as 51.6 years, range 4 to 80 years; 11 were female. The transcranial electrical stimulation MEP area under the curve for the right foot MEP was highest in the bipolar montage in 1 of 16 patients (6.3%). Meanwhile, it was highest in step 4 (M3/C1-M4/C2) in 9 of 16 patients (56.3%; P = 0.027). The highest right foot MEP area under the curve with one of the quadripolar montages was seen in 15 of 16 patients (93.8%; P = 0.0001). CONCLUSIONS: Quadripolar stimulation resulted in higher area under the curve for right foot MEP compared with conventional bipolar stimulation.

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Published In

J Clin Neurophysiol

DOI

EISSN

1537-1603

Publication Date

January 1, 2022

Volume

39

Issue

1

Start / End Page

92 / 97

Location

United States

Related Subject Headings

  • Young Adult
  • Transcranial Direct Current Stimulation
  • Retrospective Studies
  • Neurology & Neurosurgery
  • Monitoring, Intraoperative
  • Middle Aged
  • Humans
  • Female
  • Evoked Potentials, Motor
  • Electrodes
 

Citation

APA
Chicago
ICMJE
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Schwartz, S. L., Kale, E. B., Madden, D., & Husain, A. M. (2022). "Quadripolar" Transcranial Electrical Stimulation for Motor Evoked Potentials. J Clin Neurophysiol, 39(1), 92–97. https://doi.org/10.1097/WNP.0000000000000751
Schwartz, Stephanie L., Emily B. Kale, Dennis Madden, and Aatif M. Husain. “"Quadripolar" Transcranial Electrical Stimulation for Motor Evoked Potentials.J Clin Neurophysiol 39, no. 1 (January 1, 2022): 92–97. https://doi.org/10.1097/WNP.0000000000000751.
Schwartz SL, Kale EB, Madden D, Husain AM. "Quadripolar" Transcranial Electrical Stimulation for Motor Evoked Potentials. J Clin Neurophysiol. 2022 Jan 1;39(1):92–7.
Schwartz, Stephanie L., et al. “"Quadripolar" Transcranial Electrical Stimulation for Motor Evoked Potentials.J Clin Neurophysiol, vol. 39, no. 1, Jan. 2022, pp. 92–97. Pubmed, doi:10.1097/WNP.0000000000000751.
Schwartz SL, Kale EB, Madden D, Husain AM. "Quadripolar" Transcranial Electrical Stimulation for Motor Evoked Potentials. J Clin Neurophysiol. 2022 Jan 1;39(1):92–97.

Published In

J Clin Neurophysiol

DOI

EISSN

1537-1603

Publication Date

January 1, 2022

Volume

39

Issue

1

Start / End Page

92 / 97

Location

United States

Related Subject Headings

  • Young Adult
  • Transcranial Direct Current Stimulation
  • Retrospective Studies
  • Neurology & Neurosurgery
  • Monitoring, Intraoperative
  • Middle Aged
  • Humans
  • Female
  • Evoked Potentials, Motor
  • Electrodes