Elevation of cardiovascular risk by non-steroidal anti-inflammatory drugs.
Publication
, Journal Article
Anwar, A; Anwar, IJ; Delafontaine, P
Published in: Trends in cardiovascular medicine
November 2015
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most frequently used medications. NSAIDs profoundly modify prostaglandin homeostasis through inhibition of the enzyme, cyclooxygenase (COX), especially COX-2. COX-2 inhibition is associated with adverse cardiovascular outcomes as demonstrated by recent trials using this type of drug. This review explores the latest available data, including recent, randomized, clinical trials, controversies, and pathophysiology of the adverse effects of COX-inhibition.
Duke Scholars
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Published In
Trends in cardiovascular medicine
DOI
EISSN
1873-2615
ISSN
1050-1738
Publication Date
November 2015
Volume
25
Issue
8
Start / End Page
726 / 735
Related Subject Headings
- Sulfones
- Risk Assessment
- Randomized Controlled Trials as Topic
- Prevalence
- Naproxen
- Middle Aged
- Male
- Lactones
- Humans
- Homeostasis
Citation
APA
Chicago
ICMJE
MLA
NLM
Anwar, A., Anwar, I. J., & Delafontaine, P. (2015). Elevation of cardiovascular risk by non-steroidal anti-inflammatory drugs. Trends in Cardiovascular Medicine, 25(8), 726–735. https://doi.org/10.1016/j.tcm.2015.03.006
Anwar, Asif, Imran John Anwar, and Patrice Delafontaine. “Elevation of cardiovascular risk by non-steroidal anti-inflammatory drugs.” Trends in Cardiovascular Medicine 25, no. 8 (November 2015): 726–35. https://doi.org/10.1016/j.tcm.2015.03.006.
Anwar A, Anwar IJ, Delafontaine P. Elevation of cardiovascular risk by non-steroidal anti-inflammatory drugs. Trends in cardiovascular medicine. 2015 Nov;25(8):726–35.
Anwar, Asif, et al. “Elevation of cardiovascular risk by non-steroidal anti-inflammatory drugs.” Trends in Cardiovascular Medicine, vol. 25, no. 8, Nov. 2015, pp. 726–35. Epmc, doi:10.1016/j.tcm.2015.03.006.
Anwar A, Anwar IJ, Delafontaine P. Elevation of cardiovascular risk by non-steroidal anti-inflammatory drugs. Trends in cardiovascular medicine. 2015 Nov;25(8):726–735.
Published In
Trends in cardiovascular medicine
DOI
EISSN
1873-2615
ISSN
1050-1738
Publication Date
November 2015
Volume
25
Issue
8
Start / End Page
726 / 735
Related Subject Headings
- Sulfones
- Risk Assessment
- Randomized Controlled Trials as Topic
- Prevalence
- Naproxen
- Middle Aged
- Male
- Lactones
- Humans
- Homeostasis