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Metastatic squamous cell carcinoma to the pancreas: Report of an extremely rare case.

Publication ,  Journal Article
Machairas, N; Paspala, A; Schizas, D; Ntomi, V; Moris, D; Tsilimigras, DI; Misiakos, EP; Machairas, A
Published in: Molecular and clinical oncology
January 2019

Secondary pancreatic lesions are very uncommon. Resection of these metastatic lesions with a curative intent has been reported in selected patients; however, the survival benefit from these procedures has yet to be clearly determined. A 78-year-old male patient presented to our department with obstructive jaundice. Three years prior to presentation the patient had undergone right pneumonectomy, due to stage IIA, low-grade squamous cell lung carcinoma. After resection, the patient received adjuvant chemotherapy, with no evidence of local or systemic recurrence over the following 3 years. Abdominal computer tomography on admission revealed a 3-cm lesion located at the head of the pancreas, causing biliary obstruction. Endoscopic ultrasound biopsy revealed malignant cells, suspicious for squamous cell carcinoma. Due to the limited extent of the metastatic disease and in view of the patient's good condition, surgical resection was proposed and the patient successfully underwent pancreaticoduodenectomy. Histological examination of the resected specimen confirmed a squamous cell carcinoma, with an immunochemical profile similar to that of the primary lung tumor. Therefore, pancreatic resection with curative intent may be feasible in selected patients with secondary metastatic tumors. However, further studies are required in order to determine the benefit of these major procedures in terms of survival outcomes.

Duke Scholars

Published In

Molecular and clinical oncology

DOI

EISSN

2049-9469

ISSN

2049-9450

Publication Date

January 2019

Volume

10

Issue

1

Start / End Page

144 / 146

Related Subject Headings

  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis
  • 1004 Medical Biotechnology
  • 0601 Biochemistry and Cell Biology
 

Citation

APA
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MLA
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Machairas, N., Paspala, A., Schizas, D., Ntomi, V., Moris, D., Tsilimigras, D. I., … Machairas, A. (2019). Metastatic squamous cell carcinoma to the pancreas: Report of an extremely rare case. Molecular and Clinical Oncology, 10(1), 144–146. https://doi.org/10.3892/mco.2018.1756
Machairas, Nikolaos, Anna Paspala, Dimitrios Schizas, Vasileia Ntomi, Dimitrios Moris, Diamantis I. Tsilimigras, Evangelos P. Misiakos, and Anastasios Machairas. “Metastatic squamous cell carcinoma to the pancreas: Report of an extremely rare case.Molecular and Clinical Oncology 10, no. 1 (January 2019): 144–46. https://doi.org/10.3892/mco.2018.1756.
Machairas N, Paspala A, Schizas D, Ntomi V, Moris D, Tsilimigras DI, et al. Metastatic squamous cell carcinoma to the pancreas: Report of an extremely rare case. Molecular and clinical oncology. 2019 Jan;10(1):144–6.
Machairas, Nikolaos, et al. “Metastatic squamous cell carcinoma to the pancreas: Report of an extremely rare case.Molecular and Clinical Oncology, vol. 10, no. 1, Jan. 2019, pp. 144–46. Epmc, doi:10.3892/mco.2018.1756.
Machairas N, Paspala A, Schizas D, Ntomi V, Moris D, Tsilimigras DI, Misiakos EP, Machairas A. Metastatic squamous cell carcinoma to the pancreas: Report of an extremely rare case. Molecular and clinical oncology. 2019 Jan;10(1):144–146.

Published In

Molecular and clinical oncology

DOI

EISSN

2049-9469

ISSN

2049-9450

Publication Date

January 2019

Volume

10

Issue

1

Start / End Page

144 / 146

Related Subject Headings

  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis
  • 1004 Medical Biotechnology
  • 0601 Biochemistry and Cell Biology