Microbe Profile: Cryptococcus neoformans species complex.
Publication
, Journal Article
Bahn, Y-S; Sun, S; Heitman, J; Lin, X
Published in: Microbiology (Reading)
September 2020
Cryptococcus neoformans is a lethal fungus disguised in a polysaccharide coat. It can remain dormant in the host for decades prior to reactivation, causing systemic cryptococcosis in humans and other mammals. Cryptococcus deploys a multitude of traits to adapt to and survive within the host, including immunosuppression, an ability to replicate intra- and extra-cellularly in phagocytes, changes in morphology and ploidy, a predilection to infect the CNS, and the capacity to utilize neurotransmitters and unique carbon sources available in the brain. These pathogenic strategies displayed by this fungus might have evolved through its interactions with microbial predators in the environment.
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Published In
Microbiology (Reading)
DOI
EISSN
1465-2080
Publication Date
September 2020
Volume
166
Issue
9
Start / End Page
797 / 799
Location
England
Related Subject Headings
- Virulence
- Phylogeny
- Microbiology
- Humans
- Genome, Fungal
- Cryptococcus neoformans
- Cryptococcosis
- Animals
- Adaptation, Physiological
Citation
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MLA
NLM
Bahn, Y.-S., Sun, S., Heitman, J., & Lin, X. (2020). Microbe Profile: Cryptococcus neoformans species complex. Microbiology (Reading), 166(9), 797–799. https://doi.org/10.1099/mic.0.000973
Bahn, Yong-Sun, Sheng Sun, Joseph Heitman, and Xiaorong Lin. “Microbe Profile: Cryptococcus neoformans species complex.” Microbiology (Reading) 166, no. 9 (September 2020): 797–99. https://doi.org/10.1099/mic.0.000973.
Bahn Y-S, Sun S, Heitman J, Lin X. Microbe Profile: Cryptococcus neoformans species complex. Microbiology (Reading). 2020 Sep;166(9):797–9.
Bahn, Yong-Sun, et al. “Microbe Profile: Cryptococcus neoformans species complex.” Microbiology (Reading), vol. 166, no. 9, Sept. 2020, pp. 797–99. Pubmed, doi:10.1099/mic.0.000973.
Bahn Y-S, Sun S, Heitman J, Lin X. Microbe Profile: Cryptococcus neoformans species complex. Microbiology (Reading). 2020 Sep;166(9):797–799.
Published In
Microbiology (Reading)
DOI
EISSN
1465-2080
Publication Date
September 2020
Volume
166
Issue
9
Start / End Page
797 / 799
Location
England
Related Subject Headings
- Virulence
- Phylogeny
- Microbiology
- Humans
- Genome, Fungal
- Cryptococcus neoformans
- Cryptococcosis
- Animals
- Adaptation, Physiological