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Perspective on Epithelial-Mesenchymal Transitions in Embryos.

Publication ,  Journal Article
McClay, DR
Published in: Methods in molecular biology (Clifton, N.J.)
January 2021

The epithelial-mesenchymal transition (EMT) is a key process required for building the early body plan of metazoa. It involves coordinated and precisely timed changes in multiple cell processes such as de-adhesion, motility, invasion, and cell polarity. While much has been learned about how embryos deploy epithelial-mesenchymal transitions since Betty Hay named the process decades ago, a number of things are still not well understood. Here I will discuss some of the big questions that remain, including how is all of this controlled, how does each of the cell biological events work, and how are they so nicely coordinated with one another?

Duke Scholars

Published In

Methods in molecular biology (Clifton, N.J.)

DOI

EISSN

1940-6029

ISSN

1064-3745

Publication Date

January 2021

Volume

2179

Start / End Page

7 / 12

Related Subject Headings

  • Mesoderm
  • Humans
  • Gastrulation
  • Epithelium
  • Epithelial-Mesenchymal Transition
  • Embryo, Nonmammalian
  • Developmental Biology
  • Cell Polarity
  • Cell Movement
  • Cell Adhesion
 

Citation

APA
Chicago
ICMJE
MLA
NLM
McClay, D. R. (2021). Perspective on Epithelial-Mesenchymal Transitions in Embryos. Methods in Molecular Biology (Clifton, N.J.), 2179, 7–12. https://doi.org/10.1007/978-1-0716-0779-4_2
McClay, David R. “Perspective on Epithelial-Mesenchymal Transitions in Embryos.Methods in Molecular Biology (Clifton, N.J.) 2179 (January 2021): 7–12. https://doi.org/10.1007/978-1-0716-0779-4_2.
McClay DR. Perspective on Epithelial-Mesenchymal Transitions in Embryos. Methods in molecular biology (Clifton, NJ). 2021 Jan;2179:7–12.
McClay, David R. “Perspective on Epithelial-Mesenchymal Transitions in Embryos.Methods in Molecular Biology (Clifton, N.J.), vol. 2179, Jan. 2021, pp. 7–12. Epmc, doi:10.1007/978-1-0716-0779-4_2.
McClay DR. Perspective on Epithelial-Mesenchymal Transitions in Embryos. Methods in molecular biology (Clifton, NJ). 2021 Jan;2179:7–12.

Published In

Methods in molecular biology (Clifton, N.J.)

DOI

EISSN

1940-6029

ISSN

1064-3745

Publication Date

January 2021

Volume

2179

Start / End Page

7 / 12

Related Subject Headings

  • Mesoderm
  • Humans
  • Gastrulation
  • Epithelium
  • Epithelial-Mesenchymal Transition
  • Embryo, Nonmammalian
  • Developmental Biology
  • Cell Polarity
  • Cell Movement
  • Cell Adhesion