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Differential Diagnosis of Diarrhea in Patients With Neuroendocrine Tumors.

Publication ,  Journal Article
Eads, JR; Reidy-Lagunes, D; Soares, HP; Chan, JA; Anthony, LB; Halfdanarson, TR; Naraev, BG; Wolin, EM; Halperin, DM; Li, D; Pommier, RF ...
Published in: Pancreas
October 2020
Published version (DOI) Link to item

Patients with neuroendocrine tumors (NETs) and carcinoid syndrome experience diarrhea that can have a debilitating effect on quality of life. Diarrhea also may develop in response to other hormonal syndromes associated with NETs, surgical complications, medical comorbidities, medications, or food sensitivities. Limited guidance on the practical approach to the differential diagnosis of diarrhea in these patients can lead to delays in appropriate treatment. This clinical review and commentary underscore the complexity in identifying the etiology of diarrhea in patients with NETs. Based on our collective experience and expertise, we offer a practical algorithm to guide medical oncologists and other care providers to expedite effective management of diarrhea and related symptoms in patients with NETs.

Duke Scholars

Michael Aaron Morse
Author Michael Aaron Morse Medicine, Medical Oncology
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Published In

Pancreas

DOI

10.1097/MPA.0000000000001658

EISSN

1536-4828

Publication Date

October 2020

Volume

49

Issue

9

Start / End Page

1123 / 1130

Location

United States

Related Subject Headings

  • Quality of Life
  • Practice Guidelines as Topic
  • Neuroendocrine Tumors
  • Irritable Bowel Syndrome
  • Humans
  • Gastroenterology & Hepatology
  • Gastritis
  • Dyspepsia
  • Diarrhea
  • Diagnosis, Differential
 

Citation

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Eads, J. R., Reidy-Lagunes, D., Soares, H. P., Chan, J. A., Anthony, L. B., Halfdanarson, T. R., … from the Carcinoid Syndrome Control Collaborative, . (2020). Differential Diagnosis of Diarrhea in Patients With Neuroendocrine Tumors. Pancreas, 49(9), 1123–1130. https://doi.org/10.1097/MPA.0000000000001658
Eads, Jennifer R., Diane Reidy-Lagunes, Heloisa P. Soares, Jennifer A. Chan, Lowell B. Anthony, Thorvardur R. Halfdanarson, Boris G. Naraev, et al. “Differential Diagnosis of Diarrhea in Patients With Neuroendocrine Tumors.” Pancreas 49, no. 9 (October 2020): 1123–30. https://doi.org/10.1097/MPA.0000000000001658.
Eads JR, Reidy-Lagunes D, Soares HP, Chan JA, Anthony LB, Halfdanarson TR, et al. Differential Diagnosis of Diarrhea in Patients With Neuroendocrine Tumors. Pancreas. 2020 Oct;49(9):1123–30.
Eads, Jennifer R., et al. “Differential Diagnosis of Diarrhea in Patients With Neuroendocrine Tumors.” Pancreas, vol. 49, no. 9, Oct. 2020, pp. 1123–30. Pubmed, doi:10.1097/MPA.0000000000001658.
Eads JR, Reidy-Lagunes D, Soares HP, Chan JA, Anthony LB, Halfdanarson TR, Naraev BG, Wolin EM, Halperin DM, Li D, Pommier RF, Zacks JS, Morse MA, Metz DC, from the Carcinoid Syndrome Control Collaborative. Differential Diagnosis of Diarrhea in Patients With Neuroendocrine Tumors. Pancreas. 2020 Oct;49(9):1123–1130.

Published In

Pancreas

DOI

10.1097/MPA.0000000000001658

EISSN

1536-4828

Publication Date

October 2020

Volume

49

Issue

9

Start / End Page

1123 / 1130

Location

United States

Related Subject Headings

  • Quality of Life
  • Practice Guidelines as Topic
  • Neuroendocrine Tumors
  • Irritable Bowel Syndrome
  • Humans
  • Gastroenterology & Hepatology
  • Gastritis
  • Dyspepsia
  • Diarrhea
  • Diagnosis, Differential