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Antibiotics for Prophylaxis in the Setting of Preterm Prelabor Rupture of Membranes.

Publication ,  Journal Article
Dotters-Katz, S
Published in: Obstet Gynecol Clin North Am
December 2020

"For many years, providers have been using antibiotics to prevent infection in women who present with preterm prelabor rupture of membranes (PPROM). Given the polymicrobial nature of intra-amniotic infection, the recommended regimen includes a 7-day course of ampicillin and erythromycin, although many substitute of azithromycin. This regimen is used from viability to 34 weeks, independent of the number of fetuses present. Meta-analyses have shown that antibiotics for this indication are associated with lower rates of maternal and fetal infection, as well as longer pregnancy latency. Thus, latency antibiotics are recommended for all women with PPROM through 34 weeks of gestation."

Duke Scholars

Published In

Obstet Gynecol Clin North Am

DOI

EISSN

1558-0474

Publication Date

December 2020

Volume

47

Issue

4

Start / End Page

595 / 603

Location

United States

Related Subject Headings

  • Pregnancy Complications, Infectious
  • Pregnancy
  • Obstetrics & Reproductive Medicine
  • Infant, Newborn
  • Humans
  • Gestational Age
  • Fetal Membranes, Premature Rupture
  • Female
  • Erythromycin
  • Drug Therapy, Combination
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Dotters-Katz, S. (2020). Antibiotics for Prophylaxis in the Setting of Preterm Prelabor Rupture of Membranes. Obstet Gynecol Clin North Am, 47(4), 595–603. https://doi.org/10.1016/j.ogc.2020.08.005
Dotters-Katz, Sarah. “Antibiotics for Prophylaxis in the Setting of Preterm Prelabor Rupture of Membranes.Obstet Gynecol Clin North Am 47, no. 4 (December 2020): 595–603. https://doi.org/10.1016/j.ogc.2020.08.005.
Dotters-Katz S. Antibiotics for Prophylaxis in the Setting of Preterm Prelabor Rupture of Membranes. Obstet Gynecol Clin North Am. 2020 Dec;47(4):595–603.
Dotters-Katz, Sarah. “Antibiotics for Prophylaxis in the Setting of Preterm Prelabor Rupture of Membranes.Obstet Gynecol Clin North Am, vol. 47, no. 4, Dec. 2020, pp. 595–603. Pubmed, doi:10.1016/j.ogc.2020.08.005.
Dotters-Katz S. Antibiotics for Prophylaxis in the Setting of Preterm Prelabor Rupture of Membranes. Obstet Gynecol Clin North Am. 2020 Dec;47(4):595–603.
Journal cover image

Published In

Obstet Gynecol Clin North Am

DOI

EISSN

1558-0474

Publication Date

December 2020

Volume

47

Issue

4

Start / End Page

595 / 603

Location

United States

Related Subject Headings

  • Pregnancy Complications, Infectious
  • Pregnancy
  • Obstetrics & Reproductive Medicine
  • Infant, Newborn
  • Humans
  • Gestational Age
  • Fetal Membranes, Premature Rupture
  • Female
  • Erythromycin
  • Drug Therapy, Combination