A Pseudomonas syringae type III effector suppresses cell wall-based extracellular defense in susceptible Arabidopsis plants.
Bacterial effector proteins secreted through the type III secretion system (TTSS) play a crucial role in causing plant and human diseases. Although the ability of type III effectors to trigger defense responses in resistant plants is well understood, the disease-promoting functions of type III effectors in susceptible plants are largely enigmatic. Previous microscopic studies suggest that in susceptible plants the TTSS of plant-pathogenic bacteria transports suppressors of a cell wall-based plant defense activated by the TTSS-defective hrp mutant bacteria. However, the identity of such suppressors has remained elusive. We discovered that the Pseudomonas syringae TTSS down-regulated the expression of a set of Arabidopsis genes encoding putatively secreted cell wall and defense proteins in a salicylic acid-independent manner. Transgenic expression of AvrPto repressed a similar set of host genes, compromised defense-related callose deposition in the host cell wall, and permitted substantial multiplication of an hrp mutant. AvrPto is therefore one of the long postulated suppressors of an salicylic acid-independent, cell wall-based defense that is aimed at hrp mutant bacteria.
Duke Scholars
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Related Subject Headings
- Transcription Factors
- Salicylic Acid
- Receptors, Cell Surface
- Pseudomonas
- Plants, Genetically Modified
- Plant Diseases
- Mixed Function Oxygenases
- Gene Expression Regulation, Plant
- Gene Expression Regulation, Bacterial
- Gene Expression Profiling
Citation
Published In
DOI
EISSN
ISSN
Publication Date
Volume
Issue
Start / End Page
Related Subject Headings
- Transcription Factors
- Salicylic Acid
- Receptors, Cell Surface
- Pseudomonas
- Plants, Genetically Modified
- Plant Diseases
- Mixed Function Oxygenases
- Gene Expression Regulation, Plant
- Gene Expression Regulation, Bacterial
- Gene Expression Profiling