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New Concept of Onco-Hypertension and Future Perspectives.

Publication ,  Journal Article
Kidoguchi, S; Sugano, N; Tokudome, G; Yokoo, T; Yano, Y; Hatake, K; Nishiyama, A
Published in: Hypertension
January 2021

Owing to aging populations, the prevalence of hypertension and associated cardiovascular events has been increasing worldwide. The morbidity and mortality due to cancer have also been increasing with aging populations. Several small-molecule inhibitors have been used in cancer therapy, which have a positive impact on the prognosis and survival of patients with cancer. Consequently, the number of cancer survivors with hypertension has been rapidly increasing. Anticancer therapy, including vascular endothelial growth factor inhibitors, increases blood pressure. However, both clinical and laboratory evidence are lacking regarding optimal blood pressure control in patients with hypertension with cancer. Here, we propose the concept of onco-hypertension, which is an evolving subspecialty focused on the complex pathophysiology of hypertension and cancer. In this review, we highlight blood pressure changes in cancer, hypertension induced by anticancer therapy, and optimal blood pressure management in patients with hypertension with cancer. In addition, we discuss needed studies to further establish this new onco-hypertension concept.

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Published In

Hypertension

DOI

EISSN

1524-4563

Publication Date

January 2021

Volume

77

Issue

1

Start / End Page

16 / 27

Location

United States

Related Subject Headings

  • Risk Factors
  • Neoplasms
  • Hypertension
  • Humans
  • Cardiovascular System & Hematology
  • Blood Pressure Determination
  • Blood Pressure
  • Antineoplastic Agents
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
 

Citation

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Kidoguchi, S., Sugano, N., Tokudome, G., Yokoo, T., Yano, Y., Hatake, K., & Nishiyama, A. (2021). New Concept of Onco-Hypertension and Future Perspectives. Hypertension, 77(1), 16–27. https://doi.org/10.1161/HYPERTENSIONAHA.120.16044
Kidoguchi, Satoshi, Naoki Sugano, Gorou Tokudome, Takashi Yokoo, Yuichiro Yano, Kiyohiko Hatake, and Akira Nishiyama. “New Concept of Onco-Hypertension and Future Perspectives.Hypertension 77, no. 1 (January 2021): 16–27. https://doi.org/10.1161/HYPERTENSIONAHA.120.16044.
Kidoguchi S, Sugano N, Tokudome G, Yokoo T, Yano Y, Hatake K, et al. New Concept of Onco-Hypertension and Future Perspectives. Hypertension. 2021 Jan;77(1):16–27.
Kidoguchi, Satoshi, et al. “New Concept of Onco-Hypertension and Future Perspectives.Hypertension, vol. 77, no. 1, Jan. 2021, pp. 16–27. Pubmed, doi:10.1161/HYPERTENSIONAHA.120.16044.
Kidoguchi S, Sugano N, Tokudome G, Yokoo T, Yano Y, Hatake K, Nishiyama A. New Concept of Onco-Hypertension and Future Perspectives. Hypertension. 2021 Jan;77(1):16–27.

Published In

Hypertension

DOI

EISSN

1524-4563

Publication Date

January 2021

Volume

77

Issue

1

Start / End Page

16 / 27

Location

United States

Related Subject Headings

  • Risk Factors
  • Neoplasms
  • Hypertension
  • Humans
  • Cardiovascular System & Hematology
  • Blood Pressure Determination
  • Blood Pressure
  • Antineoplastic Agents
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology