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Roles for microtubules in the proliferative and differentiated cells of stratified epithelia.

Publication ,  Journal Article
Hlavaty, D; Lechler, T
Published in: Curr Opin Cell Biol
February 2021

While microtubule dynamics and organization have been extensively studied invitro, both biochemically and in cultured cells, recent work has begun to extend this into tissues ex vivo and organisms in vivo. Advances in genetic tools and imaging technology have allowed studies on the dynamics, function, and organization of microtubules in the stratified epithelia of the epidermis. Here, we discuss recent work that highlights the varied roles that microtubules play in supporting epidermal function. These findings demonstrate that studying microtubules in tissues has revealed not only novel aspects of epidermal biology but also new principles of microtubule regulation.

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Published In

Curr Opin Cell Biol

DOI

EISSN

1879-0410

Publication Date

February 2021

Volume

68

Start / End Page

98 / 104

Location

England

Related Subject Headings

  • Skin
  • Signal Transduction
  • Microtubules
  • Keratinocytes
  • Humans
  • Epidermal Cells
  • Developmental Biology
  • Cilia
  • Centrosome
  • Cell Differentiation
 

Citation

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Hlavaty, D., & Lechler, T. (2021). Roles for microtubules in the proliferative and differentiated cells of stratified epithelia. Curr Opin Cell Biol, 68, 98–104. https://doi.org/10.1016/j.ceb.2020.10.002
Hlavaty, Daniel, and Terry Lechler. “Roles for microtubules in the proliferative and differentiated cells of stratified epithelia.Curr Opin Cell Biol 68 (February 2021): 98–104. https://doi.org/10.1016/j.ceb.2020.10.002.
Hlavaty D, Lechler T. Roles for microtubules in the proliferative and differentiated cells of stratified epithelia. Curr Opin Cell Biol. 2021 Feb;68:98–104.
Hlavaty, Daniel, and Terry Lechler. “Roles for microtubules in the proliferative and differentiated cells of stratified epithelia.Curr Opin Cell Biol, vol. 68, Feb. 2021, pp. 98–104. Pubmed, doi:10.1016/j.ceb.2020.10.002.
Hlavaty D, Lechler T. Roles for microtubules in the proliferative and differentiated cells of stratified epithelia. Curr Opin Cell Biol. 2021 Feb;68:98–104.
Journal cover image

Published In

Curr Opin Cell Biol

DOI

EISSN

1879-0410

Publication Date

February 2021

Volume

68

Start / End Page

98 / 104

Location

England

Related Subject Headings

  • Skin
  • Signal Transduction
  • Microtubules
  • Keratinocytes
  • Humans
  • Epidermal Cells
  • Developmental Biology
  • Cilia
  • Centrosome
  • Cell Differentiation