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Management of hemostatic complications in acute leukemia: Guidance from the SSC of the ISTH.

Publication ,  Journal Article
Wang, T-F; Makar, RS; Antic, D; Levy, JH; Douketis, JD; Connors, JM; Carrier, M; Zwicker, JI
Published in: J Thromb Haemost
December 2020

Patients with acute leukemia frequently develop thrombocytopenia and hemostatic complications caused by coagulopathy. Coagulopathy complicates the management of these patients and can lead to significant morbidity and mortality. This guidance document aims to review and provide guidance on the management of hemostatic complications in adult patients with acute leukemia, addressing four main issues, including platelet transfusion, disseminated intravascular coagulation, L-asparaginase-related hypofibrinogenemia, and the use of antifibrinolytic agents.

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Published In

J Thromb Haemost

DOI

EISSN

1538-7836

Publication Date

December 2020

Volume

18

Issue

12

Start / End Page

3174 / 3183

Location

England

Related Subject Headings

  • Leukemia, Myeloid, Acute
  • Humans
  • Hemostatics
  • Disseminated Intravascular Coagulation
  • Cardiovascular System & Hematology
  • Antifibrinolytic Agents
  • Adult
  • Acute Disease
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
 

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Wang, T.-F., Makar, R. S., Antic, D., Levy, J. H., Douketis, J. D., Connors, J. M., … Zwicker, J. I. (2020). Management of hemostatic complications in acute leukemia: Guidance from the SSC of the ISTH. J Thromb Haemost, 18(12), 3174–3183. https://doi.org/10.1111/jth.15074
Wang, Tzu-Fei, Robert S. Makar, Darko Antic, Jerrold H. Levy, James D. Douketis, Jean M. Connors, Marc Carrier, and Jeffrey I. Zwicker. “Management of hemostatic complications in acute leukemia: Guidance from the SSC of the ISTH.J Thromb Haemost 18, no. 12 (December 2020): 3174–83. https://doi.org/10.1111/jth.15074.
Wang T-F, Makar RS, Antic D, Levy JH, Douketis JD, Connors JM, et al. Management of hemostatic complications in acute leukemia: Guidance from the SSC of the ISTH. J Thromb Haemost. 2020 Dec;18(12):3174–83.
Wang, Tzu-Fei, et al. “Management of hemostatic complications in acute leukemia: Guidance from the SSC of the ISTH.J Thromb Haemost, vol. 18, no. 12, Dec. 2020, pp. 3174–83. Pubmed, doi:10.1111/jth.15074.
Wang T-F, Makar RS, Antic D, Levy JH, Douketis JD, Connors JM, Carrier M, Zwicker JI. Management of hemostatic complications in acute leukemia: Guidance from the SSC of the ISTH. J Thromb Haemost. 2020 Dec;18(12):3174–3183.
Journal cover image

Published In

J Thromb Haemost

DOI

EISSN

1538-7836

Publication Date

December 2020

Volume

18

Issue

12

Start / End Page

3174 / 3183

Location

England

Related Subject Headings

  • Leukemia, Myeloid, Acute
  • Humans
  • Hemostatics
  • Disseminated Intravascular Coagulation
  • Cardiovascular System & Hematology
  • Antifibrinolytic Agents
  • Adult
  • Acute Disease
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology